MITOTIC REGIMEN IN THE PRIMARY AND METASTATIC NODES OF MAMMARY-GLAND AND CERVICAL-CARCINOMA

The mitotic regimen (mitotic activity ratios of mitosis phases and percentage of pathological mitoses) in primary and metastatic nodes of the tumor in [human] mammary gland and cervical carcinoma were studied. A similarity in the mitotic regimen in primary and metastatic nodes of the tumor was observed which was manifested in a high level of mitotic activity, predominance of metaphase over other phases of mitosis and the occurrence of similar pathological forms of mitosis. The difference between the mitotic regimen in the primary and metastatic nodes consisted of an increase in the latter of the number of pathological mitoses, mostly at the expense of K-mitoses. Three-group metaphase typical cervical carcinoma was found in all metastatic nodes of the squamous cell carcinoma of the cervix and may serve as a peculiar marker of tumors of this localization.