The Role of Endothelial Progenitor Cell in Cardiovascular Disease Risk Factors

被引：1
|
作者：
Minhajat, Rahmawati [1 ,2 ]
Nilasari, Dina [1 ]
Bakri, Syakib [1 ]
机构：
[1] Hasanuddin Univ, Fac Med, Dept Internal Med, A Bldg,5th Floor,Tamalanrea Km 11, Makassar 90245, Indonesia
[2] Hasanuddin Univ, Fac Med, Dept Histol, Makassar 90245, Indonesia
来源：
ACTA MEDICA INDONESIANA | 2015年 / 47卷 / 04期
关键词：
endothelial progenitor cell; endothelial dysfunction; vasculogenesis; reendothelialization;
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Endothelial progenitor cells (EPCs) are cell derived from bone marrow and the cells circulate in peripheral blood. These cells have characteristics similar to stem cells, but their ability to proliferate and differentiate is more limited. EPC discovery has changed the old paradigm in the field of vascular biology and it brings huge implications in medicine as EPCs can mediate the processes of vasculogenesis and maintain the vascular integrity. Increasing amount of EPC in the circulation is important since it has positive correlation with reendothelialization and neovascularization and they are closely linked to cardiovascular health. Thus, EPC could potentially be used for treatment of disease caused by endothelial dysfunction.
引用
收藏
页码：340 / 347
页数：8
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