Progestin therapy in endometriosis

被引:28
作者
Gezer, Altay [1 ]
Oral, Engin [1 ]
机构
[1] Istanbul Univ, Cerrahpasa Med Sch, Dept Obstet & Gynecol, Reprod Endocrinol & Infertil Div, Cerrahpasa PTT PK 31, TR-34301 Istanbul, Turkey
关键词
endometriosis; progesterone; progestin; therapy;
D O I
10.2217/whe.15.42
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Progestins are synthetic compounds that mimic the effects of progesteron. For over 50 years, oral progestins have been demonstrated to be effective in the treatment of endometriosis. They were reported to reduce or eliminate pain symptoms in approximately 90% of the patients. Progestins are available in many forms, including oral preparations, injections, subdermal implants and intrauterine systems. Continuous progestin use is an effective therapy for the treatment of painful symptoms associated with endometriosis but there had been no evidence of progestin use being superior to other types of treatment in endometriosis-related pain symptoms.
引用
收藏
页码:643 / 652
页数:10
相关论文
共 46 条
  • [1] Aromatase and other steroidogenic genes in endometriosis: translational aspects
    Attar, E
    Bulun, SE
    [J]. HUMAN REPRODUCTION UPDATE, 2006, 12 (01) : 49 - 56
  • [2] Visible and non-visible endometriosis at laparoscopy in fertile and infertile women and in patients with chronic pelvic pain: A prospective study
    Balasch, J
    Creus, M
    Fabregues, F
    Carmona, F
    Ordi, J
    MartinezRoman, S
    Vanrell, JA
    [J]. HUMAN REPRODUCTION, 1996, 11 (02) : 387 - 391
  • [3] Changes in quality of life after hormonal treatment of endometriosis
    Bergqvist, A
    Theorell, T
    [J]. ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA, 2001, 80 (07) : 628 - 637
  • [4] BROWN J, 2012, COCHRANE DB SYST REV, V14, DOI DOI 10.1002/14651858.CD002122.PUB2
  • [5] COMBINED HYSTEROSCOPIC AND LAPAROSCOPIC FINDINGS IN PATIENTS WITH CHRONIC PELVIC PAIN
    CARTER, JE
    [J]. JOURNAL OF THE AMERICAN ASSOCIATION OF GYNECOLOGIC LAPAROSCOPISTS, 1994, 2 (01): : 43 - 47
  • [6] Dienogest is as effective as triptorelin in the treatment of endometriosis after laparoscopic surgery: results of a prospective, multicenter, randomized study
    Cosson, M
    Querleu, D
    Donnez, J
    Madelenat, P
    Koninckx, P
    Audebert, A
    Manhes, H
    [J]. FERTILITY AND STERILITY, 2002, 77 (04) : 684 - 692
  • [7] Subcutaneous depot medroxyprogesterone acetate versus leuprolide acetate in the treatment of endometriosis-associated pain
    Crosignani, PG
    Luciano, A
    Ray, A
    Bergqvist, A
    [J]. HUMAN REPRODUCTION, 2006, 21 (01) : 248 - 256
  • [8] Clinical Management of Endometriosis
    Falcone, Tommaso
    Lebovic, Dan I.
    [J]. OBSTETRICS AND GYNECOLOGY, 2011, 118 (03) : 691 - 705
  • [9] Letrozole combined with norethisterone acetate compared with norethisterone acetate alone in the treatment of pain symptoms caused by endometriosis
    Ferrero, S.
    Camerini, G.
    Seracchioli, R.
    Ragni, N.
    Venturini, P. L.
    Remorgida, V.
    [J]. HUMAN REPRODUCTION, 2009, 24 (12) : 3033 - 3041
  • [10] Dienogest inhibits BrdU uptake with G0/G1 arrest in cultured endometriotic stromal cells
    Fu, Li
    Osuga, Yutaka
    Morimoto, Chieko
    Hirata, Tetsuya
    Hirota, Yasushi
    Yano, Tetsu
    Taketani, Yuji
    [J]. FERTILITY AND STERILITY, 2008, 89 : 1344 - 1347