PATHOGENESIS OF IDIOPATHIC SCOLIOSIS - SEPS IN CHICKEN WITH EXPERIMENTALLY-INDUCED SCOLIOSIS AND IN PATIENTS WITH IDIOPATHIC SCOLIOSIS

被引：82

作者：

MACHIDA, M

DUBOUSSET, J

IMAMURA, Y

IWAYA, T

YAMADA, T

KIMURA, J

TORIYAMA, S

机构：

[1] Department of Orthopaedic Surgery, Nihon University School of Medicine, Tokyo

[2] Department of Orthopaedic Surgery, Hospital St Vincent dePaul, Paris

[3] Department of Neurology, University of Iowa Hospitals Clinics, Iowa, IA

[4] Department of Neurology, Faculty of Medicine, Kyoto University, Kyoto

来源：

JOURNAL OF PEDIATRIC ORTHOPAEDICS | 1994年 / 14卷 / 03期

关键词：

EXPERIMENTAL SCOLIOSIS; IDIOPATHIC SCOLIOSIS; PATHOGENESIS; SOMATOSENSORY EVOKED POTENTIALS;

D O I：

10.1097/01241398-199405000-00010

中图分类号：

R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];

学科分类号：

摘要：

We studied somatosensory evoked potentials (SEPs) in 20 chickens with experimentally induced scoliosis after pinealectomy and in 100 patients with idiopathic scoliosis. We also studied 20 chickens without scoliosis and 20 healthy youngsters. In the chickens, SEPs after leg stimulation was significantly delayed in the scoliosis group compared to the controls. In patients, the latency of cortical potential (N37) after stimulation of tibial nerve was longer in the scoliosis group than in the controls. Our findings in both experimental and clinical studies strongly support the hypothesis that idiopathic scoliosis results from dysfunction in the central nervous system. The type of SEPs abnormalities described in idiopathic scoliosis suggest a pathology from the midbrain to the cortex.

引用

页码：329 / 335

页数：7

共 49 条

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