ETOMIDATE SHORTENS THE ONSET TIME OF NEUROMUSCULAR BLOCK

被引：34

作者：

GILL, RS ^{[1
]}

SCOTT, RPF ^{[1
]}

机构：

[1] ODSTOCK HOSP,DEPT ANAESTHESIA,SALISBURY SP2 8BJ,WILTS,ENGLAND

来源：

BRITISH JOURNAL OF ANAESTHESIA | 1992年 / 69卷 / 05期

关键词：

ANESTHETICS; INTRAVENOUS; ETOMIDATE; PROPOFOL; THIOPENTONE; NEUROMUSCULAR RELAXANTS; VECURONIUM; PHARMACODYNAMICS; ONSET TIME; NEUROMUSCULAR BLOCK;

D O I：

10.1093/bja/69.5.444

中图分类号：

R614 [麻醉学];

学科分类号：

100217 ;

摘要：

We have studied 30 healthy patients allocated randomly to receive thiopentone, propofol or etomidate in equipotent doses followed by vecuronium 0.1 mg kg-1. Haemodynamic variables and time to 100 % neuromuscular block were measured. The patients receiving etomidate had a significantly shorter onset time of neuromuscular block compared with those receiving the two other i.v. induction agents. There was a significant negative correlation between onset time of neuromuscular block and the maximum percent change in mean arterial pressure.

引用

页码：444 / 446

页数：3

共 12 条

[1] Booij L H, 1979, Acta Anaesthesiol Belg, V30, P219
[2] STRUCTURE - ACTION RELATIONSHIPS AMONG SOME DESACETOXY ANALOGS OF PANCURONIUM AND VECURONIUM IN THE ANESTHETIZED CAT
BOWMAN, WC
RODGER, IW
HOUSTON, J
MARSHALL, RJ
MCINDEWAR, I
[J]. ANESTHESIOLOGY, 1988, 69 (01) : 57 - 62
[3] BOWMAN WC, 1990, PHARM NEUROMUSCULAR, P16
[4] Doenicke A, 1974, Acta Anaesthesiol Belg, V25, P307
[5] EFFECT OF BLOOD-FLOW UPON ACTIVITY OF GALLAMINE TRIETHIODIDE
GOAT, VA
YEUNG, ML
BLAKENEY, C
FELDMAN, SA
[J]. BRITISH JOURNAL OF ANAESTHESIA, 1976, 48 (02) : 69 - 73
[6] GROUNDS RM, 1985, POSTGRAD MED J, V61, P90
[7] PHARMACOKINETICS AND DYNAMICS OF D-TUBOCURARINE DURING HYPOTHERMIA IN HUMANS
HAM, J
STANSKI, DR
NEWFIELD, P
MILLER, RD
[J]. ANESTHESIOLOGY, 1981, 55 (06) : 631 - 635
[8] Harrison G A, 1972, Anaesth Intensive Care, V1, P33
[9] HEMODYNAMIC-EFFECTS OF INFUSIONS OF DIISOPROPYL PHENOL (ICI-35868) DURING NITROUS-OXIDE ANESTHESIA IN MAN
PRYSROBERTS, C
DAVIES, JR
CALVERLEY, RK
GOODMAN, NW
[J]. BRITISH JOURNAL OF ANAESTHESIA, 1983, 55 (02) : 105 - 111
[10] CLINICAL COMPARISON OF ATRACURIUM AND VECURONIUM (ORG-NC-45)
ROBERTSON, EN
BOOIJ, LHDJ
FRAGEN, RJ
CRUL, JF
[J]. BRITISH JOURNAL OF ANAESTHESIA, 1983, 55 (02) : 125 - 129

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