ETOMIDATE SHORTENS THE ONSET TIME OF NEUROMUSCULAR BLOCK

被引：34

作者：

GILL, RS ^{[1
]}

SCOTT, RPF ^{[1
]}

机构：

[1] ODSTOCK HOSP,DEPT ANAESTHESIA,SALISBURY SP2 8BJ,WILTS,ENGLAND

来源：

BRITISH JOURNAL OF ANAESTHESIA | 1992年 / 69卷 / 05期

关键词：

ANESTHETICS; INTRAVENOUS; ETOMIDATE; PROPOFOL; THIOPENTONE; NEUROMUSCULAR RELAXANTS; VECURONIUM; PHARMACODYNAMICS; ONSET TIME; NEUROMUSCULAR BLOCK;

D O I：

10.1093/bja/69.5.444

中图分类号：

R614 [麻醉学];

学科分类号：

100217 ;

摘要：

We have studied 30 healthy patients allocated randomly to receive thiopentone, propofol or etomidate in equipotent doses followed by vecuronium 0.1 mg kg-1. Haemodynamic variables and time to 100 % neuromuscular block were measured. The patients receiving etomidate had a significantly shorter onset time of neuromuscular block compared with those receiving the two other i.v. induction agents. There was a significant negative correlation between onset time of neuromuscular block and the maximum percent change in mean arterial pressure.

引用

页码：444 / 446

页数：3

共 12 条

[1]

Booij L H, 1979, Acta Anaesthesiol Belg, V30, P219

[2] STRUCTURE - ACTION RELATIONSHIPS AMONG SOME DESACETOXY ANALOGS OF PANCURONIUM AND VECURONIUM IN THE ANESTHETIZED CAT [J].

BOWMAN, WC ;

RODGER, IW ;

HOUSTON, J ;

MARSHALL, RJ ;

MCINDEWAR, I .

ANESTHESIOLOGY, 1988, 69 (01) :57-62

[3]

BOWMAN WC, 1990, PHARM NEUROMUSCULAR, P16

[4]

Doenicke A, 1974, Acta Anaesthesiol Belg, V25, P307

[5] EFFECT OF BLOOD-FLOW UPON ACTIVITY OF GALLAMINE TRIETHIODIDE [J].

GOAT, VA ;

YEUNG, ML ;

BLAKENEY, C ;

FELDMAN, SA .

BRITISH JOURNAL OF ANAESTHESIA, 1976, 48 (02) :69-73

[6]

GROUNDS RM, 1985, POSTGRAD MED J, V61, P90

[7] PHARMACOKINETICS AND DYNAMICS OF D-TUBOCURARINE DURING HYPOTHERMIA IN HUMANS [J].

HAM, J ;

STANSKI, DR ;

NEWFIELD, P ;

MILLER, RD .

ANESTHESIOLOGY, 1981, 55 (06) :631-635

[8]

Harrison G A, 1972, Anaesth Intensive Care, V1, P33

[9] HEMODYNAMIC-EFFECTS OF INFUSIONS OF DIISOPROPYL PHENOL (ICI-35868) DURING NITROUS-OXIDE ANESTHESIA IN MAN [J].

PRYSROBERTS, C ;

DAVIES, JR ;

CALVERLEY, RK ;

GOODMAN, NW .

BRITISH JOURNAL OF ANAESTHESIA, 1983, 55 (02) :105-111

[10] CLINICAL COMPARISON OF ATRACURIUM AND VECURONIUM (ORG-NC-45) [J].

ROBERTSON, EN ;

BOOIJ, LHDJ ;

FRAGEN, RJ ;

CRUL, JF .

BRITISH JOURNAL OF ANAESTHESIA, 1983, 55 (02) :125-129

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