GENETIC-RELATIONSHIPS AMONG STRAINS OF NEISSERIA-MENINGITIDIS CAUSING DISEASE IN ITALY, 1984-7

被引：5

作者：

MASTRANTONIO, P

CONGIU, ME

SELANDER, RK

CAUGANT, DA

机构：

[1] PENN STATE UNIV,DEPT BIOL,UNIVERSITY PK,PA 16802

[2] NATL INST PUBL HLTH,DEPT METHODOL,OSLO 1,NORWAY

来源：

EPIDEMIOLOGY AND INFECTION | 1991年 / 106卷 / 01期

关键词：

D O I：

10.1017/S0950268800056508

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Since 1984 a change in the epidemiological pattern of meningococcal disease in Italy has occurred with a predominance of Neisseria meningitidis of serogroup C (76%), serotype 2a and a high proportion of strains resistant to sulphonamides (71%). In order to understand better the epidemiology of the group C N. meningitidis strains responsible for the disease over the last years in Italy, we studied the genetic features of phenotypically closely related strains, by enzyme electrophoresis. The results showed that the genetic and the phenotypic characteristics of the 57 strains studied were similar, suggesting the spread of a single clone during recent years in our country. This result is in agreement with the circulation of strains typical of epidemic situations, despite the decreasing incidence of meningoccal disease in Italy.

引用

页码：143 / 150

页数：8

共 18 条

[1]

ALBERTONI F, 1987, MICROBIOLOGICA, V10, P93

[2]

BOVRE K, 1983, NIPH (National Institute of Public Health) Annals (Oslo), V6, P75

[3] GENETIC-STRUCTURE OF NEISSERIA-MENINGITIDIS POPULATIONS IN RELATION TO SEROGROUP, SEROTYPE, AND OUTER-MEMBRANE PROTEIN PATTERN [J].