BETA-ENDORPHIN STIMULATES CORTICOSTERONE SYNTHESIS IN ISOLATED RAT ADRENAL-CELLS

被引：74
作者：
SHANKER, G
SHARMA, RK
机构：
[1] Department of Biochemistry, University of Tennessee Center for the Health Sciences, Memphis
来源：
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1979年 / 86卷 / 01期
关键词：
D O I：
10.1016/0006-291X(79)90373-5
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Studies are presented which demonstrate that β-endorphin induces corticosterone synthesis in isolated fasciculata cells. This activation of steroidogenesis has a lag period of 3 to 5 minutes and is cycloheximide-sensitive. The data suggest that β-endorphin exhibits steroidogenic activity by binding to the adrenocorticotropic hormone receptors of the cells. © 1979.
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页码：1 / 5
页数：5
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