INFLUENCE OF BARIUM ON CALCITONIN SECRETION IN THE PIG

被引:0
作者
PENTO, JT
机构
[1] Department of Pharmacodynamics and Toxicology, College of Pharmacy, University of Oklahoma Health Sciences Center, Oklahoma City
来源
PHARMACOLOGICAL RESEARCH COMMUNICATIONS | 1979年 / 11卷 / 03期
关键词
D O I
10.1016/S0031-6989(79)80083-1
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
The calcitonin secretagogue action of the barium ion was examined by the intravenous infusion of barium in vivo, by incubation with thyroid slices in vitro and by the perfusion of isolated whole thyroids in vitro. Plasma and media calcitonin levels were determined by means of a porcine calcitonin radioimmunoassay. The results of both the in vivo and in vitro experiments indicate that barium is capable of stimulating the calcitonin secretory system. © 1979 The Italian Pharmacological Society.
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页码:221 / 226
页数:6
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