Scientific Opinion on the safety of the proposed extension of use of erythritol (E 968) as a food additive

被引:20
作者
Aguilar, Fernando [1 ]
Crebelli, Riccardo [1 ]
Di Domenico, Alessandro [1 ]
Dusemund, Birgit [1 ]
Frutos, Maria Jose [1 ]
Galtier, Pierre [1 ]
Gott, David [1 ]
Gundert-Remy, Ursula [1 ]
Lambre, Claude [1 ]
Leblanc, Jean-Charles [1 ]
Lindtner, Oliver [1 ]
Moldeus, Peter [1 ]
Mortensen, Alicja [1 ]
Mosesso, Pasquale [1 ]
Parent-Massin, Dominique [1 ]
Oskarsson, Agneta [1 ]
Stankovic, Ivan [1 ]
Waalkens-Berendsen, Ine [1 ]
Woutersen, Rudolf Antonius [1 ]
Wright, Matthew [1 ]
Younes, Maged [1 ]
机构
[1] EFSA, Parma, Italy
关键词
food additive; sweetener; erythritol; E; 968; laxation; gastrointestinal tolerability;
D O I
10.2903/j.efsa.2015.4033
中图分类号
TS2 [食品工业];
学科分类号
0832 ;
摘要
Following a request from the European Commission, the EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS) provides here a scientific opinion on the safety of erythritol (E 968) in light of the proposed extension of use of erythritol to be added at a maximum level of 1.6 % (16 g/L) as a flavour enhancer in non-alcoholic beverages. In 1999, the Joint Food and Agriculture Organization of the United Nations/World Health Organization Expert Committee on Food Additives (JECFA) evaluated erythritol and assigned an ADI (acceptable daily intake) "not specified". In 2003, the European Union (EU) Scientific Committee on Food (SCF) concluded that erythritol is safe for use in foods. The EU approval of erythritol does not yet cover its use in beverages because the SCF opinion stated that the laxative threshold may be exceeded, especially by young consumers, through ingestion of erythritol in beverages. Based on the new data comprising a revised exposure estimate taking into account the proposed maximum level of 1.6 % erythritol in non-alcoholic beverages, the history of its use, the absorption characteristics of erythritol and the lack of adverse findings, including laxation, the ANS Panel concluded that the acute bolus consumption of erythritol via non-alcoholic beverages at a maximum level of 1.6 % would not raise concerns for laxation. (C) European Food Safety Authority, 2015
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页数:15
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共 14 条
[1]   Guidance for submission for food additive evaluations [J].
Aguilar, Fernando ;
Crebelli, Riccardo ;
Dusemund, Birgit ;
Galtier, Pierre ;
Gilbert, John ;
Gott, David ;
Gundert-Remy, Ursula ;
Konig, Jurgen ;
Lambre, Claude ;
Leblanc, Jean -Charles ;
Mortensen, Alicja ;
Mosesso, Pasquale ;
Parent-Massin, Dominique ;
Stankovic, Ivan ;
Tobback, Paul ;
Waalkens-Berendsen, Me ;
Woutersen, Rudolf Antonius ;
Wright, Matthew .
EFSA JOURNAL, 2012, 10 (07)
[2]   Plasma and urine kinetics of erythritol after oral ingestion by healthy humans [J].
Bornet, FRJ ;
Blayo, A ;
Dauchy, F ;
Slama, G .
REGULATORY TOXICOLOGY AND PHARMACOLOGY, 1996, 24 (02) :S280-S285
[3]   Gastrointestinal response and plasma and urine determinations in human subjects given erythritol [J].
Bornet, FRJ ;
Blayo, A ;
Dauchy, F ;
Slama, G .
REGULATORY TOXICOLOGY AND PHARMACOLOGY, 1996, 24 (02) :S296-S302
[4]  
COT (Committee on Toxicity of Chemicals in Food Consumer Products and the Environment), 2004, ANN REPORT, P10
[5]  
EFSA, 2010, EFSA J, V8, P1650, DOI [10.2903/j.efsa.2010.1650, DOI 10.2903/J.EFSA.2010.1650, DOI 10.2903/j.efsa.2010.1650]
[6]  
EFSA Panel on Food Additives and Nutrient Sources added to Food, 2013, EFSA Journal, V11, P3121
[7]   Effects of oral administration of erythritol on patients with diabetes [J].
Ishikawa, M ;
Miyashita, M ;
Kawashima, Y ;
Nakamura, T ;
Saitou, N ;
Modderman, J .
REGULATORY TOXICOLOGY AND PHARMACOLOGY, 1996, 24 (02) :S303-S308
[8]   Erythritol:: An interpretive summary of biochemical, metabolic, toxicological and clinical data [J].
Munro, IC ;
Bernt, WO ;
Borzelleca, JF ;
Flamm, G ;
Lynch, BS ;
Kennepohl, E ;
Bär, EA ;
Modderman, J .
FOOD AND CHEMICAL TOXICOLOGY, 1998, 36 (12) :1139-1174
[9]   Laxative threshold of sugar alcohol erythritol in human subjects [J].
Oku, T ;
Okazaki, M .
NUTRITION RESEARCH, 1996, 16 (04) :577-589
[10]  
Roberts A, 2009, GEN APPL TOXICOLOGY, V1, P147