A NOVEL METHOD FOR MEASURING MEMBRANE-WATER PARTITION-COEFFICIENTS OF HYDROPHOBIC ORGANIC-CHEMICALS - COMPARISON WITH 1-OCTANOL-WATER PARTITIONING

被引：193
作者：
GOBAS, FAPC
LAHITTETE, JM
GAROFALO, G
WAN, YS
MACKAY, D
机构：
[1] UNIV TORONTO,DEPT CHEM ENGN & APPL CHEM,TORONTO M5S 1A4,ONTARIO,CANADA
[2] ECOLE NATL SUPER CHIM,F-34075 MONTPELLIER,FRANCE
来源：
JOURNAL OF PHARMACEUTICAL SCIENCES | 1988年 / 77卷 / 03期
关键词：
D O I：
10.1002/jps.2600770317
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
引用
收藏
页码：265 / 272
页数：8
相关论文
共 45 条
[1]  
ANLIKER A, 1987, ECOTOX ENV SAFETY, V13, P43
[2]   DIFFUSION OF UNIVALENT IONS ACROSS LAMELLAE OF SWOLLEN PHOSPHOLIPIDS [J].
BANGHAM, AD ;
STANDISH, MM ;
WATKINS, JC .
JOURNAL OF MOLECULAR BIOLOGY, 1965, 13 (01) :238-+
[3]   BIOACCUMULATION OF SUPER-LIPOPHILIC CHEMICALS IN FISH [J].
BRUGGEMAN, WA ;
OPPERHUIZEN, A ;
WIJBENGA, A ;
HUTZINGER, O .
TOXICOLOGICAL AND ENVIRONMENTAL CHEMISTRY, 1984, 7 (03) :173-189
[4]   REVERSED-PHASE THIN-LAYER CHROMATOGRAPHY OF POLYNUCLEAR AROMATIC-HYDROCARBONS AND CHLORINATED BIPHENYLS - RELATIONSHIP WITH HYDROPHOBICITY AS MEASURED BY AQUEOUS SOLUBILITY AND OCTANOL WATER PARTITION-COEFFICIENT [J].
BRUGGEMAN, WA ;
VANDERSTEEN, J ;
HUTZINGER, O .
JOURNAL OF CHROMATOGRAPHY, 1982, 238 (02) :335-346
[5]   The energy and entropy of hydration of organic compounds. [J].
Butler, JAV .
TRANSACTIONS OF THE FARADAY SOCIETY, 1937, 33 (01) :0229-0236
[6]   The activities of some aliphatic alcohols and halides in non-polar solvents. [J].
Butler, JAV ;
Harrower, P .
TRANSACTIONS OF THE FARADAY SOCIETY, 1937, 33 (01) :0171-0178
[7]   APPLICATION OF THE FLORY-HUGGINS THEORY TO THE SOLUBILITY OF SOLIDS IN GLYCERYL TRIOLEATE [J].
CHIOU, CT ;
MANES, M .
JOURNAL OF THE CHEMICAL SOCIETY-FARADAY TRANSACTIONS I, 1986, 82 :243-246
[8]   CORRELATION BETWEEN LIPID PARTITION-COEFFICIENTS AND SURFACE PERMEATION IN SCHISTOSOMA-JAPONICUM [J].
CORNFORD, EM .
JOURNAL OF MEMBRANE BIOLOGY, 1982, 64 (03) :217-224
[9]   PARTITIONING AND LIPOPHILICITY IN QUANTITATIVE STRUCTURE ACTIVITY RELATIONSHIPS [J].
DEARDEN, JC .
ENVIRONMENTAL HEALTH PERSPECTIVES, 1985, 61 (SEP) :203-228
[10]   BIOLOGICAL MEMBRANES - PHYSICAL BASIS OF ION AND NONELECTROLYTE SELECTIVITY [J].
DIAMOND, JM ;
WRIGHT, EM .
ANNUAL REVIEW OF PHYSIOLOGY, 1969, 31 :581-+
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