ANALOGS OF S-ADENOSYLHOMOCYSTEINE AS POTENTIAL INHIBITORS OF BIOLOGICAL TRANSMETHYLATION - INHIBITION OF SEVERAL METHYLASES BY S-TUBERCIDINYLHOMOCYSTEINE

被引:53
作者
COWARD, JK [1 ]
BUSSOLOTTI, DL [1 ]
CHANG, CD [1 ]
机构
[1] YALE UNIV, SCH MED, DEPT PHARMACOL, NEW HAVEN, CT 06510 USA
关键词
D O I
10.1021/jm00258a011
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
引用
收藏
页码:1286 / 1289
页数:4
相关论文
共 29 条
[21]  
MIZUNO Y, 1963, J ORG CHEM, V28, P3329, DOI 10.1021/jo01047a012
[23]  
REKUNOVA VN, 1973, TETRAHEDRON LETT, P2811
[24]   STRUCTURE OF NUCLEOSIDE ANTIBIOTICS FORMYCIN FORMYCIN B AND LAURUSIN [J].
ROBINS, RK ;
TOWNSEND, LB ;
CASSIDY, F ;
GERSTER, JF ;
LEWIS, AF ;
MILLER, RL .
JOURNAL OF HETEROCYCLIC CHEMISTRY, 1966, 3 (01) :110-&
[25]   PSYCHOTOMIMETIC N-METHYLATED TRYPTAMINES - FORMATION IN BRAIN IN-VIVO AND IN-VITRO [J].
SAAVEDRA, JM ;
AXELROD, J .
SCIENCE, 1972, 175 (4028) :1365-&
[26]  
SUHADOLNIK RJ, 1970, NUCLEOSIDE ANTIBIOTI, pCH8
[27]   PYRAZOLOPYRIMIDINE NUCLEOSIDES .5. METHYLATION OF C-NUCLEOSIDE ANTIBIOTIC FORMYCIN AND STRUCTURAL ELUCIDATION OF PRODUCTS BY MAGNETIC CIRCULAR-DICHROISM SPECTROSCOPY [J].
TOWNSEND, LB ;
LONG, RA ;
MCGRAW, JP ;
MILES, DW ;
ROBINS, RK ;
EYRING, H .
JOURNAL OF ORGANIC CHEMISTRY, 1974, 39 (14) :2023-2027
[28]   INHIBITION OF TRANSFER RIBONUCLEIC-ACID METHYLATING ENZYMES BY CYTOTOXIC ANALOGS OF ADENOSINE [J].
WAINFAN, E ;
LANDSBERG, B .
BIOCHEMICAL PHARMACOLOGY, 1973, 22 (04) :493-500
[29]  
WARD DC, 1969, J BIOL CHEM, V244, P3243