Crystal structure of 2-[4-(methylsulfanyl)quinazolin-2-yl]-1-phenylethanol

被引:1
作者
El-Hiti, Gamal A. [1 ]
Smith, Keith [2 ]
Hegazy, Amany S. [2 ]
Ajarim, Mansour D. [3 ]
Kariuki, Benson M. [2 ]
机构
[1] King Saud Univ, Coll Appl Med Sci, Dept Optometry, Cornea Res Chair, POB 10219, Riyadh 11433, Saudi Arabia
[2] Cardiff Univ, Sch Chem, Cardiff CF10 3AT, S Glam, Wales
[3] Minist Interior, Criminal Evidence, Riyadh 11632, Saudi Arabia
来源
ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS | 2014年 / 70卷
关键词
crystal structure; 4-(methylsulfanyl)quinazoline derivative; hydrogen bonding;
D O I
10.1107/S1600536814019990
中图分类号
O7 [晶体学];
学科分类号
0702 ; 070205 ; 0703 ; 080501 ;
摘要
In the molecule of the title compound, C17H16N2OS, the almost planar methylsulfanylquinazoline group [the methyl C atom deviates by 0.032 (2) angstrom from the plane through the ring system] forms an interplanar angle of 76.26 (4) degrees with the plane of the phenyl group. An intramolecular O-H center dot center dot center dot N hydrogen bond is present between the quinazoline and hydroxy groups. In the crystal, molecules are stacked along the b-axis direction.
引用
收藏
页码:O1101 / +
页数:8
相关论文
共 12 条
  • [1] Agilent, 2014, CRYSALIS PRO
  • [2] Crystal structure of 2-ethylquinazoline-4(3H)-thione
    Alshammari, Mohammed B.
    Smith, Keith
    Hegazy, Amany S.
    Kariuki, Benson M.
    El-Hiti, Gamal A.
    [J]. ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2014, 70 : O953 - +
  • [3] 4-Methylsulfanyl-2-phenylquinazoline
    Alshammari, Mohammed B.
    Smith, Keith
    Hegazy, Amany S.
    Kariuki, Benson M.
    El-Hiti, Gamal A.
    [J]. ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2014, 70 : O871 - +
  • [4] Cambridge Soft, 2001, CHEMDRAW ULTR
  • [5] WinGX and ORTEP for Windows: an update
    Farrugia, Louis J.
    [J]. JOURNAL OF APPLIED CRYSTALLOGRAPHY, 2012, 45 : 849 - 854
  • [6] PREPARATION OF 4-MERCAPTO AND 4-AMINO QUINAZOLINES
    LEONARD, NJ
    CURTIN, DY
    [J]. JOURNAL OF ORGANIC CHEMISTRY, 1946, 11 (04) : 349 - 352
  • [7] Macrae CF, 2006, J APPL CRYSTALLOGR, V39, P453, DOI 10.1107/S0021 88980600731X
  • [8] UBER NITRILIUMSALZE .2. EINE NEUE CHINAZOLINSYNTHESE
    MEERWEIN, H
    LAASCH, P
    MERSCH, R
    NENTWIG, J
    [J]. CHEMISCHE BERICHTE-RECUEIL, 1956, 89 (02): : 224 - 238
  • [9] A short history of SHELX
    Sheldrick, George M.
    [J]. ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES, 2008, 64 : 112 - 122
  • [10] A simple and convenient procedure for lithiation and side-chain substitution of 2-alkyl-4-(methylthio)quinazolines and 2-alkyl-4-methoxyquinazolines
    Smith, K
    El-Hiti, GA
    Hegazy, AS
    [J]. SYNTHESIS-STUTTGART, 2005, (17): : 2951 - 2961