TOTAL YIELD MEASUREMENTS IN MATRIX-ASSISTED LASER-DESORPTION USING A QUARTZ-CRYSTAL MICROBALANCE

被引：64
作者：
QUIST, AP
HUTHFEHRE, T
SUNDQVIST, BUR
机构：
[1] Division of Ion Physics, Department of Radiation Sciences, Uppsala University, Uppsala, S-751 21
[2] George Washington University, Washington, District of Columbia
来源：
RAPID COMMUNICATIONS IN MASS SPECTROMETRY | 1994年 / 8卷 / 02期
关键词：
D O I：
10.1002/rcm.1290080204
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
A quartz crystal microbalance (QCM) is employed to determine the desorption yield of neutral particles in matrix-assisted laser desorption ionization. For ferulic acid, the matrix substance used, the QCM mass resolution of 1 ng corresponds to a detection limit of almost-equal-to 10(12) particles. Sample exposure effects are studied at different fluences by measuring the total desorption yield after consecutive laser pulses fired on the same spot on the sample. The dependence of the total yield on the fluence is studied for different angles of incidence of the laser beam. Varying the distance between the QCM and the sample yields information about the angular spread of the desorbed neutral particles. Additional information about the fluence threshold for the production of charged particles is gained by direct electronic measurements of sample charging.
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收藏
页码：149 / 154
页数：6
相关论文
共 29 条
  • [21] 2,5-DIHYDROXYBENZOIC ACID - A NEW MATRIX FOR LASER DESORPTION IONIZATION MASS-SPECTROMETRY
    STRUPAT, K
    KARAS, M
    HILLENKAMP, F
    [J]. INTERNATIONAL JOURNAL OF MASS SPECTROMETRY AND ION PROCESSES, 1991, 111 : 89 - 102
  • [22] SUBLIMATION VERSUS FRAGMENTATION IN MATRIX-ASSISTED LASER DESORPTION
    VERTES, A
    LEVINE, RD
    [J]. CHEMICAL PHYSICS LETTERS, 1990, 171 (04) : 284 - 290
  • [23] VERTES A, 1991, SCANNING MICROSCOPY, V5, P317
  • [24] HYDRODYNAMIC MODELING OF LASER PLASMA IONIZATION PROCESSES
    VERTES, A
    JUHASZ, P
    DEWOLF, M
    GIJBELS, R
    [J]. INTERNATIONAL JOURNAL OF MASS SPECTROMETRY AND ION PROCESSES, 1989, 94 (1-2): : 63 - 85
  • [25] HOMOGENEOUS BOTTLENECK MODEL OF MATRIX-ASSISTED ULTRAVIOLET-LASER DESORPTION OF LARGE MOLECULES
    VERTES, A
    GIJBELS, R
    LEVINE, RD
    [J]. RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 1990, 4 (06) : 228 - 233
  • [26] VERTES A, 1991, MICROBEAM ANAL, V26, P25
  • [27] VERTES A, 1991, NATO ASI SERIES
  • [28] WESTMAN A, IN PRESS INT J MASS
  • [29] WESTMAN A, IN PRESS
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