ERYTHROPOIETIN UMBILICAL SERUM LEVELS DURING LABOR IN WOMEN WITH PREECLAMPSIA, DIABETES, AND PRETERM LABOR

被引:15
作者
MAMOPOULOS, M
BILI, H
TSANTALI, C
ASSIMAKOPOULOS, E
MANTALENAKIS, S
FARMAKIDES, G
机构
[1] First Department of Obstetrics and Gynecology, First Department of Pediatrics, Aristotelian University of Thessaloniki, Thessaloniki
[2] Winthrop University Hospital, Mineola, New York
关键词
ERYTHROPOIETIN; DIABETICS; PREMATURITY; PREECLAMPSIA; PREGNANCY;
D O I
10.1055/s-2007-994612
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
In this study we determine the erythropoietin levels and hematocrit in 22 women with preterm labor, 21 with insulin-dependent diabetes, 22 with preeclampsia, and 20 with normal gestation. The erythropoietin level was higher in the preeclamptic group than in the diabetic group compared with the normal and premature groups. There were no hypoxic fetuses. From this study, we found that the mechanism of increased erythropoietin levels in neonates can be different from fetal hypoxia. Further studies are needed on this subject.
引用
收藏
页码:427 / 429
页数:3
相关论文
共 18 条
[1]  
Goldberg M.A., Dunning S.P., Bunn H.F., Regulation of the erythropoietin gene: evidence that the oxygen sensor is a heme protein, Science, 242, (1988)
[2]  
Zanjani E.D., Ascensao J.L., McGlave P., Et al., Studies on the liver to kidney switch of erythropoietin production, J Clin Invest, 67, (1981)
[3]  
Fisher J.W., Control of erythropoietin production, Proc Soc Exp Biol Med, 173, pp. 289-305, (1984)
[4]  
Finne P.H., Erythropoietin levels in theamniotic fluid, partic- ularly in Rh-immunized pregnancies. Acta Pediatr Scand, 53, (1964)
[5]  
Zanjani E.D., Gordon A.S., Erythropoietin production and utilization in fetal goats and sheep, Isr J Med Sci, 7, (1971)
[6]  
Ruth V., Autti-Ramo I., Granstrom M.L., Et al., Prediction of perinatal brain damage by cord plasma vasopressin, erythropoietin, and hypoxanthine values, J Pediatr, 113, (1988)
[7]  
Teramo K.A., Widness J.A., Cleinons G.K., Et al., Amniotic fluid erythropoietin correlates with umbilical plasma erythropoietin in normal and abnormal pregnancy, Obstet Gynecol, 69, (1987)
[8]  
Thomas R.M., Canning C.E., Cotes P.M., Et al., Erythropoietin and cord blood haemoglobin in the regulation of human fetal erythropoietin, Br J Obstet Gynaecol, 90, (1983)
[9]  
Widness J.A., Susa J.B., Garcia J.F., Et al., Increased erythro- poiesis and elevated erythropoietin in infants born to diabetic mothers and in hvperinsulinemic rhesus fetuses, J Clin Invest, 67, (1981)
[10]  
Stockman J.A., Anemia of prematurity, Clin Perinatol, 4, (1977)