MUTATION OF AN ASPARTATE RESIDUE IN THE INWARD RECTIFIER POTASSIUM CHANNEL ENCODED BY THE MURINE IRK1 GENE ALTERS ITS VOLTAGE-DEPENDENT AND K+-DEPENDENT GATING

被引:0
作者
STANFIELD, PR
DAVIES, NW
SHELTON, PA
KHAN, IA
BRAMMAR, WJ
STANDEN, NB
CONLEY, EC
机构
[1] UNIV LEICESTER,DEPT CELL PHYSIOL & PHARMACOL,LEICESTER LE1 9HN,LEICS,ENGLAND
[2] UNIV LEICESTER,DEPT BIOCHEM,LEICESTER LE1 9HN,ENGLAND
[3] UNIV LEICESTER,CTR MECHANISMS HUMAN TOXICITY,LEICESTER LE1 9HN,ENGLAND
来源
JOURNAL OF PHYSIOLOGY-LONDON | 1994年 / 477P卷
关键词
D O I
暂无
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
引用
收藏
页码:P86 / P87
页数:2
相关论文
共 39 条
  • [21] Modulation of Voltage-Dependent and Inward Rectifier Potassium Channels by 15-Epi-Lipoxin-A4 in Activated Murine Macrophages: Implications in Innate Immunity
    Moreno, Cristina
    Prieto, Patricia
    Macias, Alvaro
    Pimentel-Santillana, Maria
    de la Cruz, Alicia
    Traves, Paqui G.
    Bosca, Lisardo
    Valenzuela, Carmen
    [J]. JOURNAL OF IMMUNOLOGY, 2013, 191 (12) : 6136 - 6146
  • [22] Voltage-dependent gating and block by internal spermine of the murine inwardly rectifying K+ channel, Kir2.1
    Matsuda, H
    Oishi, K
    Omori, K
    [J]. JOURNAL OF PHYSIOLOGY-LONDON, 2003, 548 (02): : 361 - 371
  • [23] Voltage-dependent gating rearrangements in the intracellular T1-T1 interface of a K+ channel
    Wang, GY
    Covarrubias, M
    [J]. JOURNAL OF GENERAL PHYSIOLOGY, 2006, 127 (04) : 391 - 400
  • [24] Comparison of the open-close kinetics of the cloned inward rectifier K+ channel IRK1 and its point mutant (Q140E) in the pore region
    Guo, L
    Kubo, Y
    [J]. RECEPTORS & CHANNELS, 1998, 5 (05) : 273 - 289
  • [25] Molecular basis of the voltage-dependent gating of TREK-1, a mechano-sensitive K+ channel
    Maingret, F
    Honoré, E
    Lazdunski, M
    Patel, AJ
    [J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2002, 292 (02) : 339 - 346
  • [26] Voltage-dependent gating characteristics of the K+ channel KAT1 depend on the N and C termini
    Marten, I
    Hoshi, T
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1997, 94 (07) : 3448 - 3453
  • [27] The novel role of the N-terminus in controlling the voltage-dependent gating behavior of the potassium channel KAT1.
    Marten, I
    Hoshi, T
    [J]. BIOPHYSICAL JOURNAL, 1997, 72 (02) : MPO11 - MPO11
  • [28] The N-terminus of the K channel KAT1 controls its voltage-dependent gating by altering the membrane electric field
    Marten, I
    Hoshi, T
    [J]. BIOPHYSICAL JOURNAL, 1998, 74 (06) : 2953 - 2962
  • [29] Mutation of K234 and K236 in the Voltage-Dependent Anion Channel 1 Impairs Its Insertion into the Mitochondrial Outer Membrane
    Rowena Angeles
    Janet Devine
    Kenneth Barton
    Mitchell Smith
    Roy McCauley
    [J]. Journal of Bioenergetics and Biomembranes, 1999, 31 : 137 - 142
  • [30] Mutation of K234 and K236 in the voltage-dependent anion channel 1 impairs its insertion into the mitochondrial outer membrane
    Angeles, R
    Devine, J
    Barton, K
    Smith, M
    McCauley, R
    [J]. JOURNAL OF BIOENERGETICS AND BIOMEMBRANES, 1999, 31 (02) : 137 - 142