PREPARATION OF DISUBSTITUTED EPICHLOROHYDRINS WITH TOTAL DIASTEREOSELECTIVITY - TRANSFORMATION OF ALPHA-BROMOCARBONYL COMPOUNDS INTO ALLYL ALCOHOLS

被引：17
作者：
BARLUENGA, J
LLAVONA, L
BERNAD, PL
CONCELLON, JM
机构：
[1] Departamento de Química Organometállica, Facultad de Química, Universidad de Oviedo
来源：
TETRAHEDRON LETTERS | 1993年 / 34卷 / 19期
关键词：
D O I：
10.1016/S0040-4039(00)93410-5
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Epichlorohydrins 3 have been obtained with total diastereoselectivity from alpha-bromocarbonyl compounds and chloromethyllithium generated in situ. The treatment of compounds 3 with lithium iodide or lithium powder affords allyl alcohols 4 in a regioselective manner.
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页码：3173 / 3176
页数：4
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