HCV INFECTION IN HEMODIALYZED PATIENTS - INCIDENCE AND CORRELATION WITH DIALYTIC AGE

被引:19
作者
GIAMMARIA, U [1 ]
DEMEO, F [1 ]
ACITELLI, S [1 ]
TANCREDI, M [1 ]
DANIELE, M [1 ]
BARNABEI, R [1 ]
MASCHIO, C [1 ]
机构
[1] ULSS,ANAL CLIN LAB,LAQUILA,ITALY
来源
NEPHRON | 1992年 / 61卷 / 03期
关键词
HEPATITIS-C VIRUS; HEMODIALYSIS; VIRAL INFECTION;
D O I
10.1159/000186930
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Hemodialyzed patients mean an high-risk population for hepatitis C infection. Our work was performed to evaluate the incidence of hepatitis C virus (HCV) infection in 51 hemodialyzed patients; the presence of anti-HCV antibodies was studied using the EIA and RIBA test of 1st and 2nd generation. 18 patients (35.29%) showed anti-HCV antibodies with the 1st test; 27 patients (52.94%) showed the presence of anti-HCV antibodies using 2nd generation test. The incidence of test positivity is not related to blood transfusions while it is strictly related with dialytic age. All HCV seropositive patients show antibodies against the c22-3 protein of "virus core". The presence in serum of anti-c22-3 antibodies means that in these patients, there is viral replication.
引用
收藏
页码:335 / 336
页数:2
相关论文
共 3 条
[1]   EXPRESSION AND REPLICATION OF HEPATITIS-B VIRUS GENOME IN TRANSGENIC MICE [J].
ARAKI, K ;
MIYAZAKI, J ;
HINO, O ;
TOMITA, N ;
CHISAKA, O ;
MATSUBARA, K ;
YAMAMURA, K .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1989, 86 (01) :207-211
[2]  
MONDELLI MU, 1990, INT S VIRAL HEPATITI, P394
[3]  
YAMAGUCHI K, 1990, LANCET, V335, P1409