DETERMINATION OF PKA VALUE FOR 5,5-DIPHENYLHYDANTOIN

被引:69
作者
AGARWAL, SP
BLAKE, MI
机构
[1] Department of Pharmacy, University. of Illinois, Medical Center, Chicago, Illinois
基金
美国国家卫生研究院;
关键词
5,5‐Diphenylhydantoin—pKa' value determination; Potentiometric titration—procedure; UV spectrophotometry—procedure;
D O I
10.1002/jps.2600570836
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
The pKa' value for diphenylhydantoin was found to be 8.31 by ultraviolet spectrophotometry and 8.33 by potentiometric titration. Copyright © 1968 Wiley‐Liss, Inc., A Wiley Company
引用
收藏
页码:1434 / &
相关论文
共 6 条
[1]  
AGARWAL SL, IN PRESS
[2]  
AGARWAL SP, 1968, THESIS U ILLINOIS
[3]  
ALBERT A, 1962, IONIZATION CONSTANTS, P69
[4]   THE EFFECTS OF N-METHYLATION IN 5,5-DISUBSTITUTED DERIVATIVES OF BARBITURIC ACID, HYDANTOIN, AND 2,4-OXAZOLIDINEDIONE [J].
BUTLER, TC .
JOURNAL OF THE AMERICAN PHARMACEUTICAL ASSOCIATION, 1955, 44 (06) :367-370
[5]  
Mizutani M, 1925, Z PHYS CHEM-STOCH VE, V116, P350
[6]   Studies in the physical chemistry of amino acids, peptides, and related substances. IX. The dissociation constants of some amino acid derivatives [J].
Zief, M ;
Edsall, JT .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1937, 59 :2245-2248