TROPONIN-T FOR THE DIFFERENTIAL-DIAGNOSIS OF ISCHEMIC MYOCARDIAL DAMAGE

被引：76
作者：
COLLINSON, PO
MOSELEY, D
STUBBS, PJ
CARTER, GD
机构：
[1] W MIDDLESEX UNIV HOSP,DEPT CLIN BIOCHEM,MIDDLESEX,ENGLAND
[2] W MIDDLESEX UNIV HOSP,DEPT MED,MIDDLESEX,ENGLAND
[3] WESTMINSTER & CHARING CROSS HOSP & SCH MED,DEPT ACAD CARDIOL,LONDON,ENGLAND
[4] WESTMINSTER & CHARING CROSS HOSP & SCH MED,DEPT CHEM PATHOL,LONDON,ENGLAND
来源：
ANNALS OF CLINICAL BIOCHEMISTRY | 1993年 / 30卷
关键词：
CREATINE KINASE MB ISOENZYME; MYOCARDIAL INFARCTION; THROMBOLYSIS; ANGINA PECTORIS;
D O I：
10.1177/000456329303000102
中图分类号：
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号：
1001 ;
摘要：
The diagnostic performance of a new enzyme linked immunosorbent assay for the cardiac structural protein troponin T in the differential diagnosis of ischaemic cardiac damage was assessed. A well documented set of patients admitted to the coronary care unit of a district general hospital were studied. At a cutoff value of 0.2 mug/L, troponin T measurements 12-24 h after admission or 12-16 to 24-48 h from onset of chest pain showed an overall efficiency of 97.6% for diagnosis of proven myocardial infarction. Troponin T was not detectable in patients when ischaemic heart disease could be excluded but was present in four patients with angina. Detectable troponin T in these angina patients was associated with subsequent cardiac events.
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页码：11 / 16
页数：6
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