HIGHLY SENSITIVE DETECTION OF BETA-2 TRANSFERRIN IN RHINORRHEA AND OTORRHEA AS A MARKER FOR CEREBROSPINAL-FLUID (CSF) LEAKAGE

被引：23

作者：

FRANSEN, P ^{[1
]}

SINDIC, CJM ^{[1
]}

THAUVOY, C ^{[1
]}

LATERRE, C ^{[1
]}

STROOBANDT, G ^{[1
]}

机构：

[1] CATHOLIC UNIV LOUVAIN,NEUROCHIM LAB,B-1200 BRUSSELS,BELGIUM

来源：

ACTA NEUROCHIRURGICA | 1991年 / 109卷 / 3-4期

关键词：

BETA-2; TRANSFERRIN; CEREBROSPINAL FLUID; CSF RHINORRHEA; OTORRHEA;

D O I：

10.1007/BF01403002

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

As beta-2 transferrin is almost specific to the cerebrospinal fluid, its detection in rhinorrhea or otorrhea fluids demonstrates the occurrence of CSF fistula. We describe a highly sensitive method based on immunoaffinity-mediated capillary blotting for the detection of this cathodic isoform of transferrin in minute amounts (3-mu-l) of rhinorrhea or otorrhea fluids. Application of this method in a series of 10 patients with CSF fistula is reported.

引用

页码：98 / 101

页数：4

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