A SIMPLE PREPARATION OF 1H-1,4-DIAZEPINE-7(6H)-THIONES AND THEIR RING CONTRACTION TO 1-VINYL-2,3-DIHYDRO-1H-IMIDAZOLE-2-THIONES BY THERMAL REARRANGEMENT REACTION

被引：0

作者：

BARLUENGA, J ^{[1
]}

CARLON, RP ^{[1
]}

GONZALEZ, J ^{[1
]}

JOGLAR, J ^{[1
]}

ORTIZ, FL ^{[1
]}

FUSTERO, S ^{[1
]}

机构：

[1] UNIV VALENCIA,FAC FARM,DEPT QUIM ORGAN,E-46010 VALENCIA,SPAIN

来源：

BULLETIN DE LA SOCIETE CHIMIQUE DE FRANCE | 1992年 / 129卷 / 06期

关键词：

2-AZA-1,3-DIENES; 4+2] CYCLOADDITION REACTION; 1,2-DIHYDROPYRIDINE-4(3H)-THIONES; 1H-1,4-DIAZEPINE-7(6H)-THIONES; 1-VINYL-3H-IMIDAZOLE-2(3H)-THIONES; N-15; NMR; NOE; COLOC; HMBC; 3-21G-ASTERISK-CALCULATIONS;

D O I：

暂无

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

An efficient synthesis of 1H-1,4-diazepine-7(6H)-thiones via a tandem [4+2]-cycloaddition-ring expansion of chlorinated 2-aza-1,3-dienes with trimethylsilyl isothiocyanate is described. A thermal rearrangement of these 1,4-diazepine derivatives to 1-vinylimidazole-2(3H)-thiones has also been found. The structure all of these compounds was determined using a combination of modern NMR methods.

引用

页码：566 / 578

页数：13

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