IMMUNOTOXINS IN THE THERAPY OF CANCER - FROM BENCH TO CLINIC

被引：38
作者：
GHETIE, V
VITETTA, E
机构：
[1] UNIV TEXAS, SW MED CTR, DEPT MICROBIOL, DALLAS, TX 75235 USA
[2] UNIV TEXAS, SW MED CTR, CTR CANC IMMUNOBIOL, DALLAS, TX 75235 USA
来源：
PHARMACOLOGY & THERAPEUTICS | 1994年 / 63卷 / 03期
关键词：
IMMUNOTOXIN; MONOCLONAL ANTIBODY; CANCER; THERAPY;
D O I：
10.1016/0163-7258(94)90025-6
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
This review presents only those contributions that have progressed from the bench to the clinic using murine monoclonal antibodies coupled chemically to toxins, their subunits or ribosome-inactivating proteins. The rationale and progress in the development, characterization, preclinical testing and clinical trials are discussed.
引用
收藏
页码：209 / 234
页数：26
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