DIRECTED ORTHOLITHIATION OF PHENYLCARBAMIC ACID 1,1-DIMETHYLETHYL ESTER (N-BOC-ANILINE) - REVISION AND IMPROVEMENTS

被引：111
作者：
STANETTY, P
KOLLER, H
MIHOVILOVIC, M
机构：
[1] Institute of Organic Chemistry, Technical University, A-1060 Vienna
来源：
JOURNAL OF ORGANIC CHEMISTRY | 1992年 / 57卷 / 25期
关键词：
D O I：
10.1021/jo00051a030
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Evaluation of the results of a study, undertaken to examine the influence of the main reaction parameters (lithiation temperature, concentration, lithiating agent, and solvent) on the course of the title reaction, subsequently led to the development of an improved and more generally-applicable lithiation procedure. Hitherto unpublished stability data for solutions of t-BuLi and n-BuLi/TMEDA in diethyl ether and THF are reported for various temperatures.
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页码：6833 / 6837
页数：5
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