Misoprostol Vaginal Pessary Versus Dinoproston Vaginal Gel in Induction of Labour

Aim: To compare misoprostol vaginal pessary with dinoprostone vaginal gel to know which of these two agents is more safe and effective for induction of labour Method: A Interventional quasi experimental study was carried out in Sir Ganga Ram hospital, Lahore over a period of six months from 13th Feb, 2007 to 13th Aug, 2007. A total of 100 women at 37-42 months of gestation were assigned into two groups. Fifty women in group A received dinoprostone vaginal gel and 50 women in group B received misoprostol vaginal pessary. Results: 68% in group A and 87% in group B deliver within 24 hours of induction. 60% patients in group A and 56% in group B had spontaneous vaginal delivery, 64% patients in group A and 66% patients in group B required oxytocin for augmentation. Nausea and vomiting was observed in 8% patients in group-B with no case reported in group A. Fetal and maternal complications were also comparable in both groups. Overall babies delivered with good APGAR score at 1 & 5 minute interval. Conclusion: Both dinoprostone vaginal gel and misoprostol vaginal pessary appears to be equally safe and effective for induction of labour.