FIBROBLAST GROWTH FACTOR-INDUCED INCREASED SURVIVAL OF CHOLINERGIC MESOPONTINE NEURONS IN CULTURE

被引：21

作者：

GARCIARILL, E

DAVIES, DL

SKINNER, RD

BIEDERMANN, JA

MCHALFFEY, C

机构：

[1] Department of Anatomy, University of Arkansas for Medical Sciences, Little Rock

来源：

DEVELOPMENTAL BRAIN RESEARCH | 1991年 / 60卷 / 02期

关键词：

FIBROBLAST GROWTH FACTOR; PEDUNCULOPONTINE NUCLEUS; LATERODORSAL TEGMENTAL NUCLEUS; CHOLINERGIC NEURON; TISSUE CULTURE;

D O I：

10.1016/0165-3806(91)90056-O

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Basic fibroblast growth factor (bFGF) was found to increase the survival of immunocytochemically-identified cholinergic mesopontine neurons in dissociated cell cultures of embryonic rat midbrain. In contrast, cultures exposed to, (a) bFGF and an antibody to bFGF, (b) antibody to bFGF alone, or (c) untreated, contained approximately half the number of cholinergic neurons compared to bFGF-treated cultures.

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页码：267 / 270

页数：4

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