ANTIFUNGAL AGENTS .6. IN-VITRO ANTIFUNGAL ACTIVITIES OF HALOBENZOYL ESTERS OF CIS-[2-(1,1'-BIPHENYL-4-YL)-2-(1H-IMIDAZAOL-1-YLMETHYL)-1,3-DIOXOLAN-4-YL]CARBINOLS AND TRANS-[2-(1,1'-BIPHENYL-4-YL)-2-(1H-IMIDAZOL-1-YLMETHYL)-1,3-DIOXOLAN-4-YL]CARBINOLS

被引：0
|
作者：
STEFANCICH, G
SILVESTRI, R
PAGNOZZI, E
ARTICO, M
RETICO, A
APUZZO, G
SIMONETTI, N
机构：
[1] UNIV ROMA LA SAPIENZA,DIPARTIMENTO FARMACEUT,I-00185 ROME,ITALY
[2] UNIV ROMA LA SAPIENZA,IST MICROBIOL,I-00185 ROME,ITALY
来源：
FARMACO | 1993年 / 48卷 / 08期
关键词：
D O I：
暂无
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
The synthesis and the in vitro antifungal activities against Candida albicans and Candida spp of a number of halobenzoyl esters of cis- and trans-[2-(1,1'-biphenyl-4-yl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]carbinols is reported. Some new imidazoles were found more active than ketoconazole and sometimes as potent as bifonazole against Candida albicans. All derivatives were found scarcely active against Candida spp.
引用
收藏
页码：1103 / 1112
页数：10
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