C,O-DILITHIATED DIARYLMETHANOLS - EASY AND IMPROVED PREPARATION BY NAPHTHALENE-CATALYZED LITHIATION OF DIARYL KETONES AND REACTIVITY TOWARD ELECTROPHILES

被引：41

作者：

GUIJARRO, D ^{[1
]}

MANCHENO, B ^{[1
]}

YUS, M ^{[1
]}

机构：

[1] UNIV ALICANTE,FAC CIENCIAS,DEPT QUIM ORGAN,APDO 99,E-03080 ALICANTE,SPAIN

来源：

TETRAHEDRON | 1993年 / 49卷 / 06期

关键词：

D O I：

10.1016/S0040-4020(01)85822-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The lithiation of different diaryl ketones 1 with an excess of lithium powder and a catalytic amount (8 mol %) of naphthalene in tetrahydrofuran at -30-degrees-C leads to the formation of the corresponding dianions of the type I, with Met=Li, which react with several electrophiles (E+=MeI, EtBr, PriCHO, PhCHO, cyclohexanone, MeCN) to give, after hydrolysis, the expected substituted diarylmethanols 2.

引用

页码：1327 / 1334

页数：8

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