NADP-LINKED ISOZYMES ARE THE MAJOR FORMS OF ISOCITRATE DEHYDROGENASE IN MOUSE TYPE-1-LIKE ASTROCYTES

被引：8
作者：
JUURLINK, BHJ
机构：
[1] Department of Anatomy University of Saskatchewan, Saskatoon
来源：
LIFE SCIENCES | 1993年 / 52卷 / 13期
关键词：
D O I：
10.1016/0024-3205(93)90429-7
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
The activities of cytosolic NADP-linked and mitochondrial NADP- and NAD-linked isocitrate dehydrogenases were examined in three-week-old mouse astroglial cultures. The respective activities were found to be 57 +/- 7, 101 +/- 3 and 8 +/- 1 nmoles NAD(P)+ reduced per mg protein per min. Both dibutyryl cyclic AMP and cortisol caused a significant increase in the activity of the mitochondrial as well as cytosolic NADP-linked isozymes.
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页码：1087 / 1090
页数：4
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共 41 条
[21]   SOLUBLE CITRIC ACID CYCLE ENZYMES OF DROSOPHILA-MELANOGASTER .1. GENETICS AND ONTOGENY OF NADP-LINKED ISOCITRATE DEHYDROGENASE [J].
FOX, DJ .
BIOCHEMICAL GENETICS, 1971, 5 (01) :69-&
[22]   REGULATION OF NAD-LINKED AND NADP-LINKED ISOCITRATE DEHYDROGENASE BY HYDROCORTISONE IN THE BRAIN AND LIVER OF MALE-RATS OF VARIOUS AGES [J].
YADAV, RNS ;
SINGH, SN .
BIOCHIMICA ET BIOPHYSICA ACTA, 1980, 633 (03) :323-330
[23]   INTRACELLULAR-DISTRIBUTION OF NADP-LINKED ISOCITRATE DEHYDROGENASE, FUMARASE AND CITRATE SYNTHASE IN BOVINE HEART-MUSCLE [J].
FATANIA, HR ;
DALZIEL, K .
BIOCHIMICA ET BIOPHYSICA ACTA, 1980, 631 (01) :11-19
[24]   KINETIC-PROPERTIES OF PARTIALLY PURIFIED NADP-LINKED ISOCITRATE DEHYDROGENASE OF THE LIVER OF YOUNG AND OLD ALBINO-RATS [J].
SINGHYADAV, RN ;
SINGH, SN .
INDIAN JOURNAL OF BIOCHEMISTRY & BIOPHYSICS, 1980, 17 (04) :S33-S33
[25]   Gene analysis of an NADP-linked isocitrate dehydrogenase localized in peroxisomes of the n-alkane-assimilating yeast Candida tropicalis [J].
Kawachi, H ;
Shimizu, K ;
Atomi, H ;
Sanuki, S ;
Ueda, M ;
Tanaka, A .
EUROPEAN JOURNAL OF BIOCHEMISTRY, 1997, 250 (01) :205-211
[26]   Purification and characterization of NADP-Linked isocitrate dehydrogenase from the copper-tolerant wood-rotting basidiomycete Fomitopsis palustris [J].
Yoon, JJ ;
Hattori, T ;
Shimada, M .
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 2003, 67 (01) :114-120
[27]   EFFECT OF ADRENALECTOMY, HYDROCORTISONE AND ACTINOMYCIN-D ON ACTIVITY OF NADP-LINKED AND NAD-LINKED ISOCITRATE DEHYDROGENASE OF LIVER OF RATS OF VARIOUS AGES [J].
SINGHYADAV, RN ;
SINGH, SN .
INDIAN JOURNAL OF EXPERIMENTAL BIOLOGY, 1980, 18 (11) :1260-1262
[28]   EFFECTS OF TEMPERATURE AND HYDROSTATIC-PRESSURE ON ENZYMES OF AN ABYSSAL FISH, ANTIMORA-ROSTRATA - LIVER NADP-LINKED ISOCITRATE DEHYDROGENASE [J].
MOON, TW ;
STOREY, KB .
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY, 1975, 52 (01) :51-57
[29]   SOMATIC-CELL GENETIC ASSIGNMENT OF HUMAN GENE FOR MITOCHONDRIAL NADP-LINKED ISOCITRATE DEHYDROGENASE TO LONG ARM OF CHROMOSOME-15 [J].
SHIMIZU, N ;
GILES, RE ;
KUCHERLAPATI, RS ;
SHIMIZU, Y ;
RUDDLE, FH .
SOMATIC CELL GENETICS, 1977, 3 (01) :47-60
[30]   METABOLIC INHIBITION AND ELECTRICAL-PROPERTIES OF TYPE-1-LIKE CORTICAL ASTROCYTES [J].
HAROLD, DE ;
WALZ, W .
NEUROSCIENCE, 1992, 47 (01) :203-211
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