Association of coronary plaque burden with fractional flow reserve: should we keep attempting to derive physiology from anatomy?

被引：3

作者：

Abd, Thura T. ^{[1
]}

George, Richard T. ^{[1
]}

机构：

[1] Johns Hopkins Univ, Sch Med, Dept Med, Div Cardiol, Baltimore, MD 21205 USA

来源：

CARDIOVASCULAR DIAGNOSIS AND THERAPY | 2015年 / 5卷 / 01期

关键词：

Coronary computer tomography angiography (coronary CTA); invasive coronary angiography (ICA); fractional flow reserve (FFR); plaque burden; intermediate coronary stenosis;

D O I：

10.3978/j.issn.2223-3652.2015.01.07

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Coronary computed tomography angiography (CTA) has been used increasingly for the diagnosis of coronary artery disease over the past decade. Compared to invasive coronary angiography (ICA), coronary CTA has the ability to visualize and quantify atherosclerotic plaque both calcified and non-calcified. Traditional measures of evaluating a coronary stenosis such as diameter stenosis, area stenosis, minimal lumen diameter and minimal luminal area are limited in their ability to predict its functional significance especially when diameter stenosis ranges between 30-69% (intermediate range). Measurement of invasive fractional flow reserve (FFR) is considered the gold standard for assessment of the hemodynamic significance of a stenosis. The current study by Nakazato et al. evaluates the performance of an emerging coronary CTA-derived anatomical measure "percent aggregate plaque volume" to improve the detection of hemodynamic significant stenosis as compared with invasive FFR.

引用

页码：67 / 70

页数：4

共 20 条

[1] Phase II Safety and Clinical Comparison With Single-Photon Emission Computed Tomography Myocardial Perfusion Imaging for Detection of Coronary Artery Disease Flurpiridaz F 18 Positron Emission Tomography [J].

Berman, Daniel S. ;

Maddahi, Jamshid ;

Tamarappoo, B. K. ;

Czernin, Johannes ;

Taillefer, Raymond ;

Udelson, James E. ;

Gibson, C. Michael ;

Devine, Marybeth ;

Lazewatsky, Joel ;

Bhat, Gajanan ;

Washburn, Dana .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2013, 61 (04) :469-477

[2] Direct Comparison of Cardiac Magnetic Resonance and Multidetector Computed Tomography Stress-Rest Perfusion Imaging for Detection of Coronary Artery Disease [J].

Bettencourt, Nuno ;

Chiribiri, Amedeo ;

Schuster, Andreas ;

Ferreira, Nuno ;

Sampaio, Francisco ;

Pires-Morais, Gustavo ;

Santos, Lino ;

Melica, Bruno ;

Rodrigues, Alberto ;

Braga, Pedro ;

Azevedo, Luis ;

Teixeira, Madalena ;

Leite-Moreira, Adelino ;

Silva-Cardoso, Jose ;

Nagel, Eike ;

Gama, Vasco .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2013, 61 (10) :1099-1107

[3] A systematic review on diagnostic accuracy of CT-based detection of significant coronary artery disease [J].

d'Othee, Bertrand Janne ;

Siebert, Uwe ;

Cury, Ricardo ;

Jadvar, Hossein ;

Dunn, Edward J. ;

Hoffmann, Udo .

EUROPEAN JOURNAL OF RADIOLOGY, 2008, 65 (03) :449-461

[4] Abnormal epicardial coronary resistance in patients with diffuse atherosclerosis but "normal" coronary angiography [J].

De Bruyne, B ;

Hersbach, F ;

Pijls, NHJ ;

Bartunek, J ;

Bech, JW ;

Heyndrickx, GR ;

Gould, KL ;

Wijns, W .

CIRCULATION, 2001, 104 (20) :2401-2406

[5] QUANTITATIVE CORONARY ANGIOGRAPHY TO MEASURE PROGRESSION AND REGRESSION OF CORONARY ATHEROSCLEROSIS - VALUE, LIMITATIONS, AND IMPLICATIONS FOR CLINICAL-TRIALS [J].

DEFEYTER, PJ ;

SERRUYS, PW ;

DAVIES, MJ ;

RICHARDSON, P ;

LUBSEN, J ;

OLIVER, MF .

CIRCULATION, 1991, 84 (01) :412-423

[6] 2012 ACCF/AHA/ACP/AATS/PCNA/SCAI/STS Guideline for the Diagnosis and Management of Patients With Stable Ischemic Heart Disease [J].

Fihn, Stephan D. ;

Gardin, Julius M. ;

Abrams, Jonathan ;

Berra, Kathleen ;

Blankenship, James C. ;

Dallas, Apostolos P. ;

Douglas, Pamela S. ;

Foody, JoAnne M. ;

Gerber, Thomas C. ;

Hinderliter, Alan L. ;

King, Spencer B., III ;

Kligfield, Paul D. ;

Krumholz, Harlan M. ;

Kwong, Raymond Y. K. ;

Lim, Michael J. ;

Linderbaum, Jane A. ;

Mack, Michael J. ;

Munger, Mark A. ;

Prager, Richard L. ;

Sabik, Joseph F. ;

Shaw, Leslee J. ;

Sikkema, Joanna D. ;

Smith, Craig R. ;

Smith, Sidney C., Jr. ;

Spertus, John A., Jr. ;

Williams, Sankey V. ;

Anderson, Jeffrey L. ;

Halperin, Jonathan L. ;

Jacobs, Alice K. ;

Smith, Sidney C., Jr. ;

Adams, Cynthia D. ;

Albert, Nancy M. ;

Brindis, Ralph G. ;

Buller, Christopher E. ;

Creager, Mark A. ;

DeMets, David ;

Ettinger, Steven M. ;

Guyton, Robert A. ;

Hochman, Judith S. ;

Hunt, Sharon Ann ;

Kovacs, Richard J. ;

Kushner, Frederick G. ;

Lytle, Bruce W. ;

Nishimura, Rick A. ;

Ohman, E. Magnus ;

Page, Richard L. ;

Riegel, Barbara ;

Stevenson, William G. ;

Tarkington, Lynn G. ;

Yancy, Clyde W. .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2012, 60 (24) :E44-E164

[7] Myocardial CT Perfusion Imaging and SPEC T for the Diagnosis of Coronary Artery Disease: A Head-to-Head Comparison from the CORE320 Multicenter Diagnostic Performance Study [J].

George, Richard T. ;

Mehra, Vishal C. ;

Chen, Marcus Y. ;

Kitagawa, Kakuya ;

Arbab-Zadeh, Armin ;

Miller, Julie M. ;

Matheson, Matthew B. ;

Vavere, Andrea L. ;

Kofoed, Klaus F. ;

Rochitte, Carlos E. ;

Dewey, Marc ;

Yaw, Tan S. ;

Niinuma, Hiroyuki ;

Brenner, Winfried ;

Cox, Christopher ;

Clouse, Melvin E. ;

Lima, Joao A. C. ;

Di Carli, Marcelo .

RADIOLOGY, 2014, 272 (02) :407-416

[8] PHYSIOLOGIC BASIS FOR ASSESSING CRITICAL CORONARY STENOSIS - INSTANTANEOUS FLOW RESPONSE AND REGIONAL DISTRIBUTION DURING CORONARY HYPEREMIA AS MEASURES OF CORONARY FLOW RESERVE [J].

GOULD, KL ;

LIPSCOMB, K ;

HAMILTON, GW .

AMERICAN JOURNAL OF CARDIOLOGY, 1974, 33 (01) :87-94

[9] Coronary Anatomy to Predict Physiology Fundamental Limits [J].

Johnson, Nils P. ;

Kirkeeide, Richard L. ;

Gould, K. Lance .

CIRCULATION-CARDIOVASCULAR IMAGING, 2013, 6 (05) :817-832

[10] Physiological assessment of coronary artery disease in the cardiac catheterization laboratory - A scientific statement from the American Heart Association Committee on Diagnostic and Interventional Cardiac Catheterization, Council on Clinical Cardiology [J].

Kern, Morton J. ;

Lerman, Amir ;

Bech, Jan-Willen ;

De Bruyne, Bernard ;

Eeckhout, Eric ;

Fearon, William F. ;

Higano, Stuart T. ;

Lim, Michael J. ;

Meuwissen, Martijn ;

Piek, Jan J. ;

Pijls, Nico H. J. ;

Siebes, Maria ;

Spaan, Jos A. E. .

CIRCULATION, 2006, 114 (12) :1321-1341

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