ANALYSIS OF NONVOLATILE ORGANIC-COMPOUNDS IN WATER BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY

An analytical scheme has been developed for the isolation, separation and identification of trace levels of non-volatile organic compounds from drinking water. The work described was carried out in two parts. In the first part, the methods used for the analysis of four selected non-volatile organics are detailed and the results using high-performances liquid chromatography (HPLC), to the analysis of a wider range of non-volatile organics is described in the second part of the work. Separation of extracts was carried out by reversed-phase HPLC both on analytical and preparative scale. Preparative HPLC fractions were then examined by electron impact and field ionisation mass spectrometry in order to attempt identification of separated component. © 1979.