THE HUMAN SQUAMOUS CERVICAL-CARCINOMA CELL-LINE, HOG-1, IS RESPONSIVE TO STEROID-HORMONES

被引：7

作者：

WHITE, JO ^{[1
]}

JONES, RN ^{[1
]}

CROXTALL, JD ^{[1
]}

GLEESON, RP ^{[1
]}

KRAUSZ, T ^{[1
]}

PERVEZ, S ^{[1
]}

JAMIL, A ^{[1
]}

GUIDA, L ^{[1
]}

BEESLEY, JE ^{[1
]}

SOUTTER, WP ^{[1
]}

机构：

[1] HAMMERSMITH HOSP,ROYAL POSTGRAD MED SCH,DEPT HISTOPATHOL,LONDON W12 0HS,ENGLAND

来源：

INTERNATIONAL JOURNAL OF CANCER | 1992年 / 52卷 / 02期

关键词：

D O I：

10.1002/ijc.2910520216

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Growth of the human squamous cervical carcinoma cell line, HOG-I, was stimulated in response to oestradiol in serum-containing and chemically defined medium. The oestradiol-stimulated growth could be inhibited by 4-OH tamoxifen, progesterone and medroxyprogesterone acetate; the last 2 compounds also inhibited basal cell growth in serum-containing and chemically defined media. The data are consistent with the sensitivity of human squamous cervical cancer to sex-steroid hormones and suggest that endocrine therapies may be of benefit in this disease.

引用

页码：247 / 251

页数：5

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