WT1 - A NOVEL TUMOR SUPPRESSOR GENE INACTIVATED IN WILMS-TUMOR

被引:0
|
作者
HABER, DA [1 ]
BUCKLER, AJ [1 ]
机构
[1] MIT,CAMBRIDGE,MA 02139
关键词
WILMS TUMOR; TUMOR SUPPRESSOR GENES; KIDNEY DEVELOPMENT; ZINC FINGER GENE;
D O I
暂无
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:97 / 106
页数:10
相关论文
共 50 条
  • [21] Overexpression of the Wilms' tumor gene WT1 in de novo lung cancers
    Oji, Y
    Miyoshi, S
    Maeda, H
    Hayashi, S
    Tamaki, H
    Nakatsuka, SI
    Yao, M
    Takahashi, E
    Nakano, Y
    Hirabayashi, H
    Shintani, Y
    Oka, Y
    Tsuboi, A
    Hosen, N
    Asada, M
    Fujioka, T
    Murakami, M
    Kanato, K
    Motomura, M
    Kim, EH
    Kawakami, M
    Ikegame, K
    Ogawa, H
    Aozasa, K
    Kawase, I
    Sugiyama, H
    INTERNATIONAL JOURNAL OF CANCER, 2002, 100 (03) : 297 - 303
  • [22] HOMOZYGOUS INTRAGENIC DELETION IN THE WT1 GENE IN A SPORADIC WILMS-TUMOR ASSOCIATED WITH HIGH-LEVELS OF EXPRESSION OF A TRUNCATED TRANSCRIPT
    ALGAR, EM
    KENNEY, MT
    SIMMS, LA
    SMITH, SI
    KIDA, Y
    SMITH, PJ
    HUMAN MUTATION, 1995, 5 (03) : 221 - 227
  • [23] The development of Wilms tumor: From WT1 and microRNA to animal models
    Tian, Fang
    Yourek, Gregory
    Shi, Xiaolei
    Yang, Yili
    BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER, 2014, 1846 (01): : 180 - 187
  • [24] Appropriate Amounts and Activity of the Wilms' Tumor Suppressor Gene, wt1, Are Required for Normal Pronephros Development of Xenopus Embryos
    Shiraki, Taisei
    Hayashi, Takuma
    Ozue, Jotaro
    Watanabe, Minoru
    JOURNAL OF DEVELOPMENTAL BIOLOGY, 2022, 10 (04)
  • [25] The Wilms' tumor 1 gene: Oncogene or tumor suppressor gene?
    Menke, AL
    van der Eb, AJ
    Jochemsen, AG
    INTERNATIONAL REVIEW OF CYTOLOGY - A SURVEY OF CELL BIOLOGY, VOL 181, 1998, 181 : 151 - 212
  • [26] The paired-box transcription factor, PAX2, positively modulates expression of the Wilms' tumor suppressor gene (WT1)
    Dehbi, M
    Ghahremani, M
    Lechner, M
    Dressler, G
    Pelletier, J
    ONCOGENE, 1996, 13 (03) : 447 - 453
  • [27] The Wilms tumor suppressor Wt1 promotes cell adhesion through transcriptional activation of the α4integrin gene
    Kirschner, Karin M.
    Wagner, Nicole
    Wagner, Kay-Dietrich
    Wellmann, Sven
    Scholz, Holger
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2006, 281 (42) : 31930 - 31939
  • [28] The role of WT1 in oncogenesis: Tumor suppressor or oncogene?
    Loeb, DM
    Sukumar, S
    INTERNATIONAL JOURNAL OF HEMATOLOGY, 2002, 76 (02) : 117 - 126
  • [29] Clinical relevance of mutations in the Wilms tumor suppressor 1 gene WT1 and the cadherin-associated protein β1 gene CTNNB1 for patients with Wilms tumors
    Royer-Pokora, Brigitte
    Weirich, Angela
    Schumacher, Valerie
    Uschkereit, Constanze
    Beier, Manfred
    Leuschner, Ivo
    Graf, Norbert
    Autschbach, Frank
    Schneider, Dominique
    von Harrach, Melissa
    CANCER, 2008, 113 (05) : 1080 - 1089
  • [30] Activation of the WT1 tumor suppressor gene promoter by Pea3
    Discenza, MT
    Vaz, D
    Hassell, JA
    Pelletier, J
    FEBS LETTERS, 2004, 560 (1-3) : 183 - 191