SAPONINS FROM THE LEAVES OF GUAIACUM-OFFICINALE

Guaiacin, C, D, E and F, four new saponins, have been isolated from the leaves ofGuaiacum officinale and characterised on the basis of chemical investigation and spectroscopic studies as 3-O-[α-l-rhamnopyranosyl(1 → 2)α-l-arabinopyranosyl(3 → 1)β-d-glucopyranosyl]-30-norolean-12,20(29)-dien-28-oic acid; 3-O-[α-l-rhamnopyranosyl-(1 → 2)α-l-arabinopyranosyl(3 → 1)β-d-glucopyranosyl]-30-norolean-12,20(29)-dien-28-O-[β-d-glu copyranosyl] ester; 3-O-[β-d-glucopyranosyl(1 → 2)α-l-arabinopyranosyl(3 → 1)β-d-glucopyranosyl]-30-norolean-12,20(29)-dien-28-O-[β-d-glu copyranosyl]ester; 3-O-[β-d-glucopyranosyl(1 → 2)α-l-arabinopyranosyl(3 → 1)β-d-glucopyranosyl] oleanolic acid-28-O-[β-d-glucopyranosyl]ester. © 1990 Pergamon Press plc.