ANALYTICAL STUDIES OF METABOLISM OF TERRACLOR IN BEAGLE DOGS, RATS, AND PLANTS

被引：64
作者：
KUCHAR, EJ
GEENTY, FO
GRIFFITH, WP
THOMAS, RJ
机构：
[1] Chemicals Division, Olin Mathieson Chemical Corp., Conn. 06504, New Haven
来源：
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY | 1969年 / 17卷 / 06期
关键词：
D O I：
10.1021/jf60166a041
中图分类号：
S [农业科学];
学科分类号：
09 ;
摘要：
Tissues from beagle dogs fed Terraclor in food (PCNB, daily for up to two years) were analyzed by gas chromatography for residual PCNB, impurities, and metabolites. The data obtained are indicative that PCNB is not present in fat or tissue and the metabolic products of PCNB are pentachloroaniline (PCA) and methyl pentachlorophenyl sulfide. The presence of PCA and methyl pentachlorophenyl sulfide has been established by infrared and mass spectroscopy. Chromatographic analyses of extracts of rat tissues from rats fed PCNB and from plants grown in PCNB treated soil are indicative of an identical metabolism. © 1969, American Chemical Society. All rights reserved.
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页码：1237 / &
相关论文
共 7 条
[1]   METABOLISM OF PENTACHLORONITROBENZENE AND 2-3-4-6-TETRACHLORONITROBENZENE AND THE FORMATION OF MERCAPTURIC ACIDS IN THE RABBIT [J].
BETTS, JJ ;
JAMES, SP ;
THORPE, WV .
BIOCHEMICAL JOURNAL, 1955, 61 (04) :611-617
[2]  
FINNEGAN JK, 1958, ARCH INT PHARMACOD T, V114, P38
[3]   NEW TECHNIQUE FOR PREPARATION OF KBR PELLETS FROM MICROSAMPLES [J].
GARNER, HR ;
PACKER, H .
APPLIED SPECTROSCOPY, 1968, 22 (02) :122-&
[4]   PENTACHLORONITROBENZENE RESIDUES IN POTATOES [J].
GORBACH, S ;
WAGNER, U .
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 1967, 15 (04) :654-&
[5]  
METHRATTA MP, 1967, J AGR FOOD CHEM, V15, P648
[6]   FATE OF 4,6-DINITRO-2-ISOBUTYLPHENOL 2-CHLORO-4,6-BIS-(ETHYLAMINO)-S-TRIAZINE AND PENTACHLORONITROBENZENE IN DAIRY COW [J].
STJOHN, LE ;
AMMERING, JW ;
WAGNER, DG ;
WARNER, RG ;
LISK, DJ .
JOURNAL OF DAIRY SCIENCE, 1965, 48 (04) :502-+
[7]  
WILLIAMS RT, 1959, DETOXICATION MECHANI, P428
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