MicroRNAs-from metastasis prediction to metastasis prevention?

被引：7

作者：

Abba, Mohammed ^{[1
,2
]}

Patil, Nitin ^{[1
,2
]}

Leupold, Joerg Hendrik ^{[1
,2
]}

Allgayer, Heike ^{[1
,2
]}

机构：

[1] Heidelberg Univ, Dept Expt Surg, Med Fac Mannheim, Theodor Kutzer Ufer 1-3, D-68135 Mannheim, Germany

[2] Heidelberg Univ, Ctr Biomed & Med Technol Mannheim CBTM, Med Fac Mannheim, Ludolf Krehl Str 6, D-68135 Mannheim, Germany

来源：

MOLECULAR & CELLULAR ONCOLOGY | 2016年 / 3卷 / 02期

关键词：

Cancer; EMT; FOXN3; microRNA; metastasis; stem cell;

D O I：

10.1080/23723556.2015.1074336

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Recently, we suggested the microRNA (miR) landscape defining metastasis. The first miR-driven network orchestrating invasion, intravasation, and metastasis was confirmed independently across several malignancies, suggesting a rather general principle for metastasis regulation. We hope that our data will stimulate the field in terms of further hypothesis generation, metastasis prediction, and metastasis prevention.

引用

页数：3

共 7 条

[1] miR-34: from bench to bedside [J].

Agostini, Massimiliano ;

Knight, Richard A. .

ONCOTARGET, 2014, 5 (04) :872-881

[2] The shaping and functional consequences of the microRNA landscape in breast cancer [J].

Dvinge, Heidi ;

Git, Anna ;

Graef, Stefan ;

Salmon-Divon, Mali ;

Curtis, Christina ;

Sottoriva, Andrea ;

Zhao, Yongjun ;

Hirst, Martin ;

Armisen, Javier ;

Miska, Eric A. ;

Chin, Suet-Feung ;

Provenzano, Elena ;

Turashvili, Gulisa ;

Green, Andrew ;

Ellis, Ian ;

Aparicio, Sam ;

Caldas, Carlos .

NATURE, 2013, 497 (7449) :378-382

[3] MicroRNA-135b promotes lung cancer metastasis by regulating multiple targets in the Hippo pathway and LZTS1 [J].

Lin, Ching-Wen ;

Chang, Yih-Leong ;

Chang, Yu-Chiuan ;

Lin, Jau-Chen ;

Chen, Chun-Chi ;

Pan, Szu-Hua ;

Wu, Chen-Tu ;

Chen, Hsuan-Yu ;

Yang, Shuenn-Chen ;

Hong, Tse-Ming ;

Yang, Pan-Chyr .

NATURE COMMUNICATIONS, 2013, 4

[4] A Systematic Approach to Defining the microRNA Landscape in Metastasis [J].

Mudduluru, Giridhar ;

Abba, Mohammed ;

Batliner, Jasmin ;

Patil, Nitin ;

Scharp, Maike ;

Lunavat, Taral R. ;

Leupold, Joerg Hendrik ;

Oleksiuk, Olga ;

Juraeva, Dilafruz ;

Thiele, Wilko ;

Rothley, Melanie ;

Benner, Axel ;

Ben-Neriah, Yinon ;

Sleeman, Jonathan ;

Allgayer, Heike .

CANCER RESEARCH, 2015, 75 (15) :3010-3019

[5] Oncomine 3.0: Genes, pathways, and networks in a collection of 18,000 cancer gene expression profiles [J].

Rhodes, Daniel R. ;

Kalyana-Sundaram, Shanker ;

Mahavisno, Vasudeva ;

Varambally, Radhika ;

Yu, Jianjun ;

Briggs, Benjamin B. ;

Barrette, Terrence R. ;

Anstet, Matthew J. ;

Kincead-Beal, Colleen ;

Kulkarni, Prakash ;

Varambally, Sooryanaryana ;

Ghoshy, Debashis ;

Chinnaiyan, Arul M. .

NEOPLASIA, 2007, 9 (02) :166-180

[6] The pre-metastatic niche: finding common ground [J].

Sceneay, Jaclyn ;

Smyth, Mark J. ;

Moeller, Andreas .

CANCER AND METASTASIS REVIEWS, 2013, 32 (3-4) :449-464

[7] MicroRNA-135b Promotes Cancer Progression by Acting as a Downstream Effector of Oncogenic Pathways in Colon Cancer [J].

Valeri, Nicola ;

Braconi, Chiara ;

Gasparini, Pierluigi ;

Murgia, Claudio ;

Lampis, Andrea ;

Paulus-Hock, Viola ;

Hart, Jonathan R. ;

Ueno, Lynn ;

Grivennikov, Sergei I. ;

Lovat, Francesca ;

Paone, Alessio ;

Cascione, Luciano ;

Sumani, Khlea M. ;

Veronese, Angelo ;

Fabbri, Muller ;

Carasi, Stefania ;

Alder, Hansjuerg ;

Lanza, Giovanni ;

Gafa', Roberta ;

Moyer, Mary P. ;

Ridgway, Rachel A. ;

Cordero, Julia ;

Nuovo, Gerard J. ;

Frankel, Wendy L. ;

Rugge, Massimo ;

Fassan, Matteo ;

Groden, Joanna ;

Vogt, Peter K. ;

Karin, Michael ;

Sansom, Owen J. ;

Croce, Carlo M. .

CANCER CELL, 2014, 25 (04) :469-483

← 1 →