RECOMBINANT WHOLE CELLS AS CATALYSTS FOR THE ENZYMATIC-SYNTHESIS OF OLIGOSACCHARIDES AND GLYCOPEPTIDES

被引：23

作者：

HERRMANN, GF ^{[1
]}

WANG, P ^{[1
]}

SHEN, GJ ^{[1
]}

WONG, CH ^{[1
]}

机构：

[1] Scripps Res Inst, RES INST, DEPT CHEM, LA JOLLA, CA 92037 USA

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 1994年 / 33卷 / 12期

关键词：

D O I：

10.1002/anie.199412411

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An easier, faster, cheaper approach to the enzymatic synthesis of oligosaccharides would be to employ whole cells rather than purified enzymes. In this report recombinant E. coli cells mediate the mannosylation of monosaccharides and glycopeptides. It was also proven that the relevant enzyme, mannosyl transferase, does not leak from the periplasmic space of the cells into the medium. Copyright © 1994 by VCH Verlagsgesellschaft mbH, Germany

引用

页码：1241 / 1242

页数：2

共 31 条

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