INTRASELLAR PITUITARY TISSUE PRESSURE, TUMOR SIZE AND ENDOCRINE STATUS - AN INTERNATIONAL COMPARISON IN 107 PATIENTS

被引：24
作者：
LEES, PD
FAHLBUSCH, R
ZRINZO, A
PICKARD, JD
机构：
[1] UNIV ERLANGEN NURNBERG,DEPT NEUROSURG,W-8520 ERLANGEN,GERMANY
[2] ADDENBROOKES HOSP,ACAD NEUROSURG UNIT,CAMBRIDGE CB2 2QQ,ENGLAND
来源：
BRITISH JOURNAL OF NEUROSURGERY | 1994年 / 8卷 / 03期
关键词：
ENDOCRINE FUNCTION; INTRASELLAR PRESSURE; PITUITARY ADENOMA;
D O I：
10.3109/02688699409029619
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
In a two-centre study, intrasellar pituitary tissue pressure was measured at transsphenoidal surgery in 107 patients with pituitary adenomas or intrasellar cysts. 'Normal' ISP in patients under anaesthesia with small microadenomas (< 5 mm diameter) or a partial empty sella was 12 +/- 3 mmHg. Raised ISP (> 15 mmHg) was found in 75 % of cases. The highest pressures were recorded in tumours with parasellar invasion (30 +/- 2; p < 0.01) irrespective of size and extension in other directions. In non-invasive lesions there was no correlation between the level of raised ISP and tumour size. Hypopituitarism and stalk compression syndrome were both associated with higher ISP than patients with normal pituitary function.
引用
收藏
页码：313 / 318
页数：6
相关论文
共 9 条
[1]  
ANTUNES JL, 1983, NEUROSURGERY, V21, P492
[2]   ANGIOGRAPHIC DELINEATION OF SELLAR AND PARASELLAR MASSES [J].
BAKER, HL .
RADIOLOGY, 1972, 104 (01) :67-&
[3]   MICROADENOMAS OF THE HUMAN PITUITARY AND THEIR VASCULARIZATION [J].
GORCZYCA, W ;
HARDY, J .
NEUROSURGERY, 1988, 22 (01) :1-6
[4]   PRESSURE AND BLOOD-FLOW IN PITUITARY-ADENOMAS MEASURED DURING TRANSSPHENOIDAL SURGERY [J].
KRUSE, A ;
ASTRUP, J ;
COLD, GE ;
HANSEN, HH .
BRITISH JOURNAL OF NEUROSURGERY, 1992, 6 (04) :333-342
[5]   SECRETION OF NEURON-SPECIFIC ENOLASE, PROLACTIN, GROWTH-HORMONE, LUTEINIZING-HORMONE AND FOLLICLE-STIMULATING-HORMONE BY FUNCTIONLESS AND ENDOCRINE-ACTIVE PITUITARY-TUMORS INVITRO [J].
LAWTON, NF ;
EVANS, AJ ;
PICKARD, JD ;
PERRY, S ;
DAVIES, B .
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 1986, 49 (05) :574-580
[6]   HYPERPROLACTINEMIA, INTRASELLAR PITUITARY TISSUE PRESSURE, AND THE PITUITARY-STALK COMPRESSION SYNDROME [J].
LEES, PD ;
PICKARD, JD .
JOURNAL OF NEUROSURGERY, 1987, 67 (02) :192-196
[7]   EFFECTS OF BROMOCRIPTINE ON PITUITARY-TUMOR SIZE [J].
MCGREGOR, AM ;
SCANLON, MF ;
HALL, R ;
HALL, K .
BRITISH MEDICAL JOURNAL, 1979, 2 (6192) :700-703
[8]   PRIMARY ANGIOGRAPHIC FINDINGS IN PITUITARY ADENOMAS [J].
POWELL, DF ;
BAKER, HL ;
LAWS, ER .
RADIOLOGY, 1974, 110 (03) :589-595
[9]   PITUITARY MICROCIRCULATION - PHYSIOLOGICAL-ASPECTS AND CLINICAL IMPLICATIONS - A LASER-DOPPLER FLOW STUDY DURING TRANSSPHENOIDAL ADENOMECTOMY [J].
STEINMEIER, R ;
FAHLBUSCH, R ;
POWERS, AD ;
DOTTERL, A ;
BUCHFELDER, M .
NEUROSURGERY, 1991, 29 (01) :47-54
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