SELECTIN LIGANDS

被引：951
作者：
VARKI, A [1 ]
机构：
[1] UNIV CALIF SAN DIEGO, DIV CELLULAR & MOLEC MED, LA JOLLA, CA 92093 USA
来源：
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 1994年 / 91卷 / 16期
关键词：
D O I：
10.1073/pnas.91.16.7390
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
The selectins initiate many critical interactions among blood cells. The volume of information and diversity of opinions on the nature of the biologically relevant ligands for selectins is remarkable. This review analyzes the matter and suggests the hypothesis that at least some of the specificity may involve recognition of ''clustered saccharide patches.''
引用
收藏
页码：7390 / 7397
页数：8
相关论文
共 132 条
[31]   HIGH-AFFINITY BINDING OF THE LEUKOCYTE ADHESION MOLECULE L-SELECTIN TO 3'-SULFATED-LEA AND 3'-SULFATED-LEX OLIGOSACCHARIDES AND THE PREDOMINANCE OF SULFATE IN THIS INTERACTION DEMONSTRATED BY BINDING-STUDIES WITH A SERIES OF LIPID-LINKED OLIGOSACCHARIDES [J].
GREEN, PJ ;
TAMATANI, T ;
WATANABE, T ;
MIYASAKA, M ;
HASEGAWA, A ;
KISO, M ;
YUEN, CT ;
STOLL, MS ;
FEIZI, T .
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1992, 188 (01) :244-251
[32]   SELECTIN GMP-140 (CD62, PADGEM) BINDS TO SIALOSYL-LEA AND SIALOSYL-LEX, AND SULFATED GLYCANS MODULATE THIS BINDING [J].
HANDA, K ;
NUDELMAN, ED ;
STROUD, MR ;
SHIOZAWA, T ;
HAKOMORI, S .
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1991, 181 (03) :1223-1230
[33]   INTERACTION OF P-SELECTIN (CD62) AND ITS CELLULAR LIGAND - ANALYSIS OF CRITICAL RESIDUES [J].
HOLLENBAUGH, D ;
BAJORATH, J ;
STENKAMP, R ;
ARUFFO, A .
BIOCHEMISTRY, 1993, 32 (12) :2960-2966
[34]   A LYMPHOCYTE HOMING RECEPTOR (L-SELECTIN) MEDIATES THE INVITRO ATTACHMENT OF LYMPHOCYTES TO MYELINATED TRACTS OF THE CENTRAL-NERVOUS-SYSTEM [J].
HUANG, K ;
GEOFFROY, JS ;
SINGER, MS ;
ROSEN, SD .
JOURNAL OF CLINICAL INVESTIGATION, 1991, 88 (05) :1778-1783
[35]   CHEMICAL-ENZYMATIC SYNTHESIS AND CONFORMATIONAL-ANALYSIS OF SIALYL LEWIS-X AND DERIVATIVES [J].
ICHIKAWA, Y ;
LIN, YC ;
DUMAS, DP ;
SHEN, GJ ;
GARCIAJUNCEDA, E ;
WILLIAMS, MA ;
BAYER, R ;
KETCHAM, C ;
WALKER, LE ;
PAULSON, JC ;
WONG, CH .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1992, 114 (24) :9283-9298
[36]   FURTHER CHARACTERIZATION OF THE INTERACTION BETWEEN L-SELECTIN AND ITS ENDOTHELIAL LIGANDS [J].
IMAI, Y ;
LASKY, LA ;
ROSEN, SD .
GLYCOBIOLOGY, 1992, 2 (04) :373-381
[37]  
IMAI Y, 1993, NATURE, V361, P555
[38]   IDENTIFICATION OF A CARBOHYDRATE-BASED ENDOTHELIAL LIGAND FOR A LYMPHOCYTE HOMING RECEPTOR [J].
IMAI, Y ;
SINGER, MS ;
FENNIE, C ;
LASKY, LA ;
ROSEN, SD .
JOURNAL OF CELL BIOLOGY, 1991, 113 (05) :1213-1221
[39]  
ITO K, 1994, IN PRESS GLYCOCONJUG
[40]   WHY ARE PROTEINS O-GLYCOSYLATED [J].
JENTOFT, N .
TRENDS IN BIOCHEMICAL SCIENCES, 1990, 15 (08) :291-294
12345678910