BIOTRANSFORMATION OF ARTEANNUIC ACID INTO ARTEANNUIN-B AND ARTEMISININ IN ARTEMISIA-ANNUA

被引：61

作者：

SANGWAN, RS ^{[1
]}

AGARWAL, K ^{[1
]}

LUTHRA, R ^{[1
]}

THAKUR, RS ^{[1
]}

SINGHSANGWAN, N ^{[1
]}

机构：

[1] CENT INST MED & AROMAT PLANTS, POST BAG 1, PO RSM, LUCKNOW, INDIA

来源：

PHYTOCHEMISTRY | 1993年 / 34卷 / 05期

关键词：

ARTEMISIA-ANNUA; COMPOSITAE; ARTEMISININ BIOSYNTHESIS; IN-VIVO; IN-VITRO CONVERSION;

D O I：

10.1016/0031-9422(91)80019-W

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

In Artemisia annua, [C-14]arteannuic acid was incorporated into arteannuin-B as well as artemisinin, both in vivo and in a cell free system. Fe2+, 2-oxoglutarate, and peroxidase-H2O2 enhanced the incorporations under in vitro conditions. The results suggest that arteannuic acid might be a common precursor for arteannuin-B and artemisinin synthesis.

引用

页码：1301 / 1302

页数：2

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