BIOTRANSFORMATION OF ARTEANNUIC ACID INTO ARTEANNUIN-B AND ARTEMISININ IN ARTEMISIA-ANNUA

被引：61

作者：

SANGWAN, RS ^{[1
]}

AGARWAL, K ^{[1
]}

LUTHRA, R ^{[1
]}

THAKUR, RS ^{[1
]}

SINGHSANGWAN, N ^{[1
]}

机构：

[1] CENT INST MED & AROMAT PLANTS, POST BAG 1, PO RSM, LUCKNOW, INDIA

来源：

PHYTOCHEMISTRY | 1993年 / 34卷 / 05期

关键词：

ARTEMISIA-ANNUA; COMPOSITAE; ARTEMISININ BIOSYNTHESIS; IN-VIVO; IN-VITRO CONVERSION;

D O I：

10.1016/0031-9422(91)80019-W

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

In Artemisia annua, [C-14]arteannuic acid was incorporated into arteannuin-B as well as artemisinin, both in vivo and in a cell free system. Fe2+, 2-oxoglutarate, and peroxidase-H2O2 enhanced the incorporations under in vitro conditions. The results suggest that arteannuic acid might be a common precursor for arteannuin-B and artemisinin synthesis.

引用

页码：1301 / 1302

页数：2

共 14 条

[1] TERPENE EPOXIDASES AND EPOXIDE HYDRATASES FROM CULTURES OF JASMINUM-OFFICINALE
BANTHORPE, DV
OSBORNE, MJ
[J]. PHYTOCHEMISTRY, 1984, 23 (04) : 905 - 907
[2] BARZ W, 1981, BIOCH PLANTS, V7, P35
[3] NATURALLY-OCCURRING CADINENES
BORDOLOI, M
SHUKLA, VS
NATH, SC
SHARMA, RP
[J]. PHYTOCHEMISTRY, 1989, 28 (08) : 2007 - 2037
[4] ON THE POSSIBLE ROLE OF QUINGHAO ACID IN THE BIOSYNTHESIS OF ARTEMISININ
ELFERALY, FS
ALMESHAL, IA
ALYAHYA, MA
HIFNAWY, MS
[J]. PHYTOCHEMISTRY, 1986, 25 (12) : 2777 - 2778
[5] HOAGLAND D. R., 1950, Circular. California Agricultural Experiment Station, V347
[6] ENZYME-SYSTEM GENERATION OF SINGLET (1-DELTAG) MOLECULAR-OXYGEN OBSERVED DIRECTLY BY 1.0-1,8-MU-M LUMINESCENCE SPECTROSCOPY
KHAN, AU
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1983, 105 (24) : 7195 - 7197
[7] QINGHAOSU (ARTEMISININ) - AN ANTIMALARIAL DRUG FROM CHINA
KLAYMAN, DL
[J]. SCIENCE, 1985, 228 (4703) : 1049 - 1055
[8] EFFECT OF STEROL INHIBITORS ON THE INCORPORATION OF C-14 ISOPENTENYL PYROPHOSPHATE INTO ARTEMISININ BY A CELL-FREE SYSTEM FROM ARTEMISIA-ANNUA TISSUE-CULTURES AND PLANTS
KUDAKASSERIL, GJ
LAM, L
STABA, EJ
[J]. PLANTA MEDICA, 1987, (03) : 280 - 284
[9] FORMATION OF ARTEMISININ IN ARTEMISIA-ANNUA DURING ONE VEGETATION PERIOD
LIERSCH, R
SOICKE, H
STEHR, C
TULLNER, HU
[J]. PLANTA MEDICA, 1986, (05) : 387 - 390
[10] NAIR MSR, 1985, INT RES C NATURAL PR

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