HYDROXYLATION OF DEHYDROEPIANDROSTERONE IN HUMAN SCALP HAIR-FOLLICLES

被引：10
|
作者：
VERMORKEN, AJM
GOOS, CMAA
HENDERSON, PT
BLOEMENDAL, H
机构：
[1] CATHOLIC UNIV NIJMEGEN,DEPT BIOCHEM,NIJMEGEN,NETHERLANDS
[2] CATHOLIC UNIV NIJMEGEN,DEPT HUMAN GENET,NIJMEGEN,NETHERLANDS
来源：
BRITISH JOURNAL OF DERMATOLOGY | 1979年 / 100卷 / 06期
关键词：
D O I：
10.1111/j.1365-2133.1979.tb08074.x
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
The dehydroepiandrosterone hydroxylatmg enzyme system in the hair follicle has been characterized. It is found in the particulate fraction of the follicle, and is inhibited by carbon monoxide and the cytochrome P450 inhibitor metyraponc, and appears to be dependent upon NADPH. In these major characteristics the hair follicle enzyme is very similar to the liver monooxygcnase system. Copyright © 1979, Wiley Blackwell. All rights reserved
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页码：693 / 698
页数：6
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