EFFECT OF CLENBUTEROL ON RECOVERY OF MUSCLE MASS AND CARCASS PROTEIN-CONTENT FOLLOWING EXPERIMENTAL HYPERTHYROIDISM IN OLD RATS

被引：6
作者：
CARTER, WJ [1 ]
LYNCH, ME [1 ]
机构：
[1] UNIV ARKANSAS MED SCI HOSP,DEPT MED,LITTLE ROCK,AR 72205
来源：
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-PHYSIOLOGY | 1994年 / 108卷 / 2-3期
关键词：
CLENBUTEROL; MUSCLE MASS; CARCASS PROTEIN; HYPERTHYROIDISM; OLD RATS;
D O I：
10.1016/0300-9629(94)90110-4
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The beta(2)-adrenoceptor agonist, clenbuterol, has hastened the recovery of skeletal muscle and carcass weights and carcass protein stores lost during experimental hyperthyroidism in 24-month-old rats. Daily injection of 6.5 mu g T-3 per 100 g body weight for 2 weeks and 4.0 mu g for the third week caused a 17-22% reduction in total body, carcass and combined hindlimb muscle weights, and a 16-21% reduction in carcass protein stores. Feeding diet containing 10 mg clenbuterol per kg during a 3-week recovery period caused complete restoration of these parameters to euthyroid control levels while the feeding control diet did not.
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收藏
页码：387 / 394
页数：8
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