ACTIN-CONTAINING MATRIX ASSOCIATED WITH THE PLASMA-MEMBRANE OF MURINE TUMOR AND LYMPHOID-CELLS

被引:204
|
作者
MESCHER, MF [1 ]
JOSE, MJL [1 ]
BALK, SP [1 ]
机构
[1] HARVARD UNIV, SCH MED, DEPT PATHOL, BOSTON, MA 02115 USA
关键词
D O I
10.1038/289139a0
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
A detergent-insoluble matrix was isolated from murine tumor cell and lymphocyte plasma membranes. The major components of this matrix include actin and 4 additional proteins not previously identified as cytoskeletal proteins. Labeling studies indicate that the matrix is located on the inner face of the plasma membrane. A cell-surface glycoprotein, 5''-nucleotidase, remains associated with the isolated matrix.
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页码:139 / 144
页数:6
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