STRUCTURE OF N,N'-DIMETHYL-4,4'-BIPYRIDYLIUM DICHLORIDE DIHYDRATE

被引：31
作者：
COUSSON, A
BACHET, B
KOKEL, B
HUBERTHABART, M
机构：
[1] UNIV PARIS 06,MINERAL & CRISTALLOG LAB,CNRS,LA 09,F-75230 PARIS 05,FRANCE
[2] INST CURIE,CHERCHEURS,INSERM,F-75231 PARIS 05,FRANCE
来源：
ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS | 1993年 / 49卷
关键词：
D O I：
10.1107/S0108270191015019
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
C12H14N22+.2Cl-.2H2O, M(r) = 293, triclinic, P1BAR, a = 9.696 (3), b = 11.322 (4), c = 7.076 (3) angstrom, alpha = 100.68 (4), beta = 93.40 (3), gamma = 107.04 (4)degrees, V = 724 (6) angstrom3, Z = 2, D(x) = 1.344 Mg m-3, lambda(Cu Kalpha) = 1.5418 angstrom, mu = 4.4 mm-1, F(000) = 308, room temperature, R = 0.052 for 2201 independent reflections. N,N'-dimethyl-4,4'-bipyridylium dichloride (or paraquat, viologen) like mitoguazone (an anticancer drug), affects the polyamine uptake systems, a potential target in cancer chemotherapy. The description of the three-dimensional structure of this ion should allow a better assessment of the structure-activity relationship of these bioactive molecules.
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页码：942 / 943
页数：2
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