THE INTRAMUCOSAL DISTRIBUTION OF GASTRIC ALCOHOL-DEHYDROGENASE AND ALDEHYDE DEHYDROGENASE-ACTIVITY IN RATS

被引：13
|
作者：
MALY, IP
ARNOLD, M
KRIEGER, K
ZALEWSKA, M
SASSE, D
机构：
[1] UNIV BASEL, INST ANAT, PESTALOZZISTR 20, CH-4056 BASEL, SWITZERLAND
[2] MED ACAD WROCLAW, INFECT DIS CLIN, PL-53416 WROCLAW, POLAND
来源：
HISTOCHEMISTRY | 1992年 / 98卷 / 05期
关键词：
D O I：
10.1007/BF00270015
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Using qualitative and microquantitative histochemical techniques, alcohol dehydrogenase and aldehyde dehydrogenase activity was studied in the gastric mucosa of male and female rats. Alcohol dehydrogenase was demonstrated by staining reactions with maximum activity in surface and neck cells and with clearly weaker activity also in parietal cells. Aldehyde dehydrogenase could be detected in surface and neck cells, and also to a comparable degree in the parietal cells. Quantitative analyses of microdissected samples yielded high values. for alcohol dehydrogenase activity exclusively in the superficial part of the gastric mucosa, whereas low-K(m) aldehyde dehydrogenase activity showed a decreasing gradient from the surface to the deeper parts of the mucosa. Sex differences could not be confirmed.
引用
收藏
页码：311 / 315
页数：5
相关论文
共 50 条
12345