BIOTIN AND CHOLINE IN FOODS - NUTRITIONAL IMPORTANCE AND METHODS OF ANALYSIS - REVIEW

Biotin and choline are essential nutrients for many animals and man. Biotin has been shown to be an active component of several enzymes. The nutrient is involved in regulating fatty acid synthesis and also influences carbohydrate metabolism. Generally, the need for biotin in the human body is easily met through the dietary supply combined with endogenous synthesis by the gut microflora. Choline plays a crucial role in maintaining cellular membrane structure and permeability and in transporting fat in the bloodstream. The body can synthesise choline provided adequate amounts of precursors, folic acid and vitamin B12 are available. A choline deficiency is only possible when both the amount of choline in the diet and the supply of nutrients required for de novo synthesis are limiting. This review discusses the nutritional importance of biotin and choline and methods of analysis for these nutrients. © 1978.