EFFECTS OF ALPRAZOLAM ON T-CELL IMMUNOSUPPRESSIVE RESPONSE TO SURGICAL STRESS IN MICE

被引：23

作者：

FREIREGARABAL, M ^{[1
]}

BELMONTE, A ^{[1
]}

ORALLO, F ^{[1
]}

COUCEIRO, J ^{[1
]}

NUNEZ, MJ ^{[1
]}

机构：

[1] UNIV SANTIAGO DE COMPOSTELA, FAC MED, DEPT PHARMACOL, E-15705 SANTIAGO, SPAIN

来源：

CANCER LETTERS | 1991年 / 58卷 / 03期

关键词：

STRESS; IMMUNITY; LYMPHOCYTES-T; BLASTIC RESPONSE; ALPRAZOLAM; ANXIOLYTICS; ADRENOCORTICOTROPIC HORMONE;

D O I：

10.1016/0304-3835(91)90098-3

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Mice submitted to surgical stress induced by laparotomy and treated with chronic alprazolam (1 mg/kg) showed a reduction in stress-induced suppression of thymus and spleen cellularity, as well as in peripheral T lymphocyte population. The blastic response of spleen lymphoid cells was also assessed and found to partially supress the inhibitory effect of surgery.

引用

页码：183 / 187

页数：5

共 28 条

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