ELECTROCARDIOGRAPHIC FINDINGS OF WBN KOB RATS

被引:6
作者
MACHIDA, K [1 ]
DOI, K [1 ]
KABURAKI, M [1 ]
SUGANO, S [1 ]
机构
[1] UNIV TOKYO, FAC AGR, DEPT ANIM ENVIRONM PHYSIOL, BUNKYO KU, TOKYO 113, JAPAN
关键词
ECG Changes; WBN/Kob Rat;
D O I
10.1258/002367790780866155
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
Electrocardiographical (RCG) investigations were carried out on 4 and 12 week old WBN/Kob and Wistar male rats. In comparison with Wistar rats which showed ECG findings typical of those of normal rats, WBN/Kob rats showed significantly larger QRS complex amplitude, smaller T wave amplitude, longer QRS duration, and longer QT interval at 4 weeks of age. This tendency became clearer at 12 weeks of age. There were no changes in serum inorganic ion concentrations or cardiac histopathology suggestive of these ECG changes in WBN/Kob rats. These ECG findings in WBN/Kob rats are considered to be a hereditary characteristic of the strain. © 1990, Royal Society of Medicine Press. All rights reserved.
引用
收藏
页码:288 / 291
页数:4
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