FAMILIAL ISLET CELL TUMORS IN VON HIPPEL-LINDAUS DISEASE

被引：0

作者：

HULL, MT ^{[1
]}

WARFEL, KA ^{[1
]}

MULLER, J ^{[1
]}

HIGGINS, JT ^{[1
]}

机构：

[1] MED COLL OHIO,DEPT MED,TOLEDO,OH 43699

来源：

CANCER | 1979年 / 44卷 / 04期

关键词：

D O I：

10.1002/1097-0142(197910)44:4<1523::AID-CNCR2820440452>3.0.CO;2-0

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Von Hippel‐Lindau's Disease is an hereditary disorder characterized by the development of hemangioblastomas of the cerebellum and retina and a variety of cystic and neoplastic lesions of other organs such as renal cell carcinoma and pheochromocytoma. In a single generation of a family with Von Hippel‐Lindau's disease, all four siblings developed lesions classically associated with the complex. Additionally, two of the four developed islet cell tumors of the pancreas, one in one patient and five in the other. While a familial incidence of islet cell tumors is known in multiple endocrine adenomatosis, type I and Zollinger‐Ellison syndrome, such a familial occurrence has been heretofore unrecorded in the Von Hippel‐Lindau complex. Copyright © 1979 American Cancer Society

引用

页码：1523 / 1526

页数：4

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