Response to sunitinib (Sutent) in chemotherapy refractory clear cell ovarian cancer

被引：4

作者：

Alifrangis, C. ^{[1
]}

Thornton, A. ^{[1
]}

Fotopoulou, C. ^{[3
]}

Krell, J. ^{[1
,2
]}

Gabra, H. ^{[1
,2
]}

机构：

[1] Hammersmith Hosp, Dept Med Oncol, Du Cane Rd, London W12 0HS, England

[2] Imperial Coll London, Div Canc, London, England

[3] Imperial Coll London, Dept Gynaecol, London, England

来源：

GYNECOLOGIC ONCOLOGY REPORTS | 2016年 / 18卷

基金：

英国医学研究理事会;

关键词：

Targeted therapy; Clear cell; Drug resistance;

D O I：

10.1016/j.gore.2016.11.001

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

[No abstract available]

引用

页码：42 / 44

页数：3

共 15 条

[1] IL6-STAT3-HIF Signaling and Therapeutic Response to the Angiogenesis Inhibitor Sunitinib in Ovarian Clear Cell Cancer [J].

Anglesio, Michael S. ;

George, Joshy ;

Kulbe, Hagen ;

Friedlander, Michael ;

Rischin, Danny ;

Lemech, Charlotte ;

Power, Jeremy ;

Coward, Jermaine ;

Cowin, Prue A. ;

House, Colin M. ;

Chakravarty, Probir ;

Gorringe, Kylie L. ;

Campbell, Ian G. ;

Okamoto, Aikou ;

Birrer, Michael J. ;

Huntsman, David G. ;

de Fazio, Anna ;

Kalloger, Steve E. ;

Balkwill, Frances ;

Gilks, C. Blake ;

Bowtell, David D. .

CLINICAL CANCER RESEARCH, 2011, 17 (08) :2538-2548

[2] A phase II trial (AGO 2.11) in platinum-resistant ovarian cancer: a randomized multicenter trial with sunitinib (SU11248) to evaluate dosage, schedule, tolerability, toxicity and effectiveness of a multitargeted receptor tyrosine kinase inhibitor monotherapy [J].

Baumann, K. H. ;

du Bois, A. ;

Meier, W. ;

Rau, J. ;

Wimberger, P. ;

Sehouli, J. ;

Kurzeder, C. ;

Hilpert, F. ;

Hasenburg, A. ;

Canzler, U. ;

Hanker, L. C. ;

Hillemanns, P. ;

Richter, B. ;

Wollschlaeger, K. ;

Dewitz, T. ;

Bauerschlag, D. ;

Wagner, U. .

ANNALS OF ONCOLOGY, 2012, 23 (09) :2265-2271

[3] A phase II study of sunitinib in patients with recurrent epithelial ovarian and primary peritoneal carcinoma: an NCIC Clinical Trials Group Study [J].

Biagi, J. J. ;

Oza, A. M. ;

ChalChal, H. I. ;

Grimshaw, R. ;

Ellard, S. L. ;

Lee, U. ;

Hirte, H. ;

Sederias, J. ;

Ivy, S. P. ;

Eisenhauer, E. A. .

ANNALS OF ONCOLOGY, 2011, 22 (02) :335-340

[4] Synthetic lethality by targeting EZH2 methyltransferase activity in ARID1A-mutated cancers [J].

Bitler, Benjamin G. ;

Aird, Katherine M. ;

Garipov, Azat ;

Li, Hua ;

Amatangelo, Michael ;

Kossenkov, Andrew V. ;

Schultz, David C. ;

Liu, Qin ;

Shih, Ie-Ming ;

Conejo-Garcia, Jose R. ;

Speicher, David W. ;

Zhang, Rugang .

NATURE MEDICINE, 2015, 21 (03) :231-+

[5] Coexistent ARID1A-PIK3CA mutations promote ovarian clear-cell tumorigenesis through pro-tumorigenic inflammatory cytokine signalling [J].

Chandler, Ronald L. ;

Damrauer, Jeffrey S. ;

Raab, Jesse R. ;

Schisler, Jonathan C. ;

Wilkerson, Matthew D. ;

Didion, John P. ;

Starmer, Joshua ;

Serber, Daniel ;

Yee, Della ;

Xiong, Jessie ;

Darr, David B. ;

de Villena, Fernando Pardo-Manuel ;

Kim, William Y. ;

Magnuson, Terry .

NATURE COMMUNICATIONS, 2015, 6

[6] A phase I trial combining carboplatin/doxorubicin with tocilizumab, an anti-IL-6R monoclonal antibody, and interferon-α2b in patients with recurrent epithelial ovarian cancer [J].

Dijkgraaf, E. M. ;

Santegoets, S. J. A. M. ;

Reyners, A. K. L. ;

Goedemans, R. ;

Wouters, M. C. A. ;

Kenter, G. G. ;

van Erkel, A. R. ;

van Poelgeest, M. I. E. ;

Nijman, H. W. ;

van der Hoeven, J. J. M. ;

Welters, M. J. P. ;

van der Burg, S. H. ;

Kroep, J. R. .

ANNALS OF ONCOLOGY, 2015, 26 (10) :2141-2149

[7] Molecular Profiling of Clear Cell Ovarian Cancers Identifying Potential Treatment Targets for Clinical Trials [J].

Friedlander, Michael L. ;

Russell, Kenneth ;

Millis, Sherri ;

Gatalica, Zoran ;

Bender, Ryan ;

Voss, Andreas .

INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER, 2016, 26 (04) :648-654

[8] Clear-cell carcinoma of the ovary [J].

Fujiwara, K. ;

Shintani, D. ;

Nishikawa, T. .

ANNALS OF ONCOLOGY, 2016, 27 :50-52

[9] Frequent Mutations of Chromatin Remodeling Gene ARID1A in Ovarian Clear Cell Carcinoma [J].

Jones, Sian ;

Wang, Tian-Li ;

Shih, Ie-Ming ;

Mao, Tsui-Lien ;

Nakayama, Kentaro ;

Roden, Richard ;

Glas, Ruth ;

Slamon, Dennis ;

Diaz, Luis A., Jr. ;

Vogelstein, Bert ;

Kinzler, Kenneth W. ;

Velculescu, Victor E. ;

Papadopoulos, Nickolas .

SCIENCE, 2010, 330 (6001) :228-231

[10] Surgical and Medical Treatment of Clear Cell Ovarian Cancer Results From the Multicenter Italian Trials in Ovarian Cancer (MITO) 9 Retrospective Study [J].

Magazzino, Francescapaola ;

Katsaros, Dionyssios ;

Ottaiano, Alessandro ;

Gadducci, Angiolo ;

Pisano, Carmela ;

Sorio, Roberto ;

Rabaiotti, Emanuela ;

Scambia, Giovanni ;

Cormio, Gennaro ;

Scarampi, Luca ;

Greggi, Stefano ;

Savarese, Antonella ;

Marinaccio, Marco ;

Scollo, Paolo ;

Pignata, Sandro .

INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER, 2011, 21 (06) :1063-1070

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