MINIMAL KINETIC MECHANISM AND GENERAL EQUATION FOR DEUTERIUM-ISOTOPE EFFECTS ON ENZYMIC REACTIONS - UNCERTAINTY IN DETECTING A RATE-LIMITING STEP

被引：75

作者：

NORTHROP, DB

机构：

来源：

BIOCHEMISTRY | 1981年 / 20卷 / 14期

关键词：

D O I：

10.1021/bi00517a017

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

收藏

页码：4056 / 4061

页数：6

相关论文

共 12 条

[1] ABELES RH, 1960, J BIOL CHEM, V235, P835
[2] Cleland W W, 1980, Methods Enzymol, V64, P104
[3] KINETICS OF ENZYME-CATALYZED REACTIONS WITH 2 OR MORE SUBSTRATES OR PRODUCTS .1. NOMENCLATURE AND RATE EQUATIONS
CLELAND, WW
[J]. BIOCHIMICA ET BIOPHYSICA ACTA, 1963, 67 (01) : 104 - &
[4] PARTITION ANALYSIS AND CONCEPT OF NET RATE CONSTANTS AS TOOLS IN ENZYME-KINETICS
CLELAND, WW
[J]. BIOCHEMISTRY, 1975, 14 (14) : 3220 - 3224
[5] CLELAND WW, 1963, BIOCHIM BIOPHYS ACTA, V67, P188
[6] KINETICS OF ENZYME-CATALYZED REACTIONS WITH 2 OR MORE SUBSTRATES OR PRODUCTS .2. INHIBITION - NOMENCLATURE AND THEORY
CLELAND, WW
[J]. BIOCHIMICA ET BIOPHYSICA ACTA, 1963, 67 (02) : 173 - &
[7] JENCKS WP, 1969, CATALYSIS CHEM ENZYM, P475
[8] Northrop D. B., 1977, ISOTOPE EFFECTS ENZY, P122
[9] STEADY-STATE ANALYSIS OF KINETIC ISOTOPE-EFFECTS IN ENZYMIC REACTIONS
NORTHROP, DB
[J]. BIOCHEMISTRY, 1975, 14 (12) : 2644 - 2651
[10] OLEARY MH, 1978, TRANSITION STATES BI, P294